"Myosin Type V" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of myosin involved in organelle transport and membrane targeting. It is abundantly found in nervous tissue and neurosecretory cells. The heavy chains of myosin V contain unusually long neck domains that are believed to aid in translocating molecules over large distances.
Descriptor ID |
D024701
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MeSH Number(s) |
D05.750.078.730.475.750 D08.811.277.040.025.193.750.875 D12.776.220.525.475.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myosin Type V".
Below are MeSH descriptors whose meaning is more specific than "Myosin Type V".
This graph shows the total number of publications written about "Myosin Type V" by people in this website by year, and whether "Myosin Type V" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 1 | 0 | 1 |
2006 | 1 | 1 | 2 |
2007 | 1 | 0 | 1 |
2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Myosin Type V" by people in Profiles.
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Gunther LK, Rohde JA, Tang W, Cirilo JA, Marang CP, Scott BD, Thomas DD, Debold EP, Yengo CM. FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V. J Biol Chem. 2020 12 18; 295(51):17383-17397.
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Zhan S, Zhang W, Niitep?ld K, Hsu J, Haeger JF, Zalucki MP, Altizer S, de Roode JC, Reppert SM, Kronforst MR. The genetics of monarch butterfly migration and warning colouration. Nature. 2014 Oct 16; 514(7522):317-21.
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Yoshii A, Zhao JP, Pandian S, van Zundert B, Constantine-Paton M. A Myosin Va mutant mouse with disruptions in glutamate synaptic development and mature plasticity in visual cortex. J Neurosci. 2013 May 08; 33(19):8472-82.
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Koles K, Nunnari J, Korkut C, Barria R, Brewer C, Li Y, Leszyk J, Zhang B, Budnik V. Mechanism of evenness interrupted (Evi)-exosome release at synaptic boutons. J Biol Chem. 2012 May 11; 287(20):16820-34.
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Jin Y, Sultana A, Gandhi P, Franklin E, Hamamoto S, Khan AR, Munson M, Schekman R, Weisman LS. Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex. Dev Cell. 2011 Dec 13; 21(6):1156-70.
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Heuck A, Fetka I, Brewer DN, H?ls D, Munson M, Jansen RP, Niessing D. The structure of the Myo4p globular tail and its function in ASH1 mRNA localization. J Cell Biol. 2010 May 03; 189(3):497-510.
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Sugimoto Y, Sato O, Watanabe S, Ikebe R, Ikebe M, Wakabayashi K. Reverse conformational changes of the light chain-binding domain of myosin V and VI processive motor heads during and after hydrolysis of ATP by small-angle X-ray solution scattering. J Mol Biol. 2009 Sep 18; 392(2):420-35.
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Li XD, Jung HS, Wang Q, Ikebe R, Craig R, Ikebe M. The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va. Proc Natl Acad Sci U S A. 2008 Jan 29; 105(4):1140-5.
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Watanabe S, Watanabe TM, Sato O, Awata J, Homma K, Umeki N, Higuchi H, Ikebe R, Ikebe M. Human myosin Vc is a low duty ratio nonprocessive motor. J Biol Chem. 2008 Apr 18; 283(16):10581-92.
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Li XD, Jung HS, Mabuchi K, Craig R, Ikebe M. The globular tail domain of myosin Va functions as an inhibitor of the myosin Va motor. J Biol Chem. 2006 Aug 04; 281(31):21789-21798.