"Cross-Priming" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I-restricted activation of CD8-POSITIVE LYMPHOCYTES resulting from ANTIGEN PRESENTATION of exogenous ANTIGENS (cross-presentation). This is in contrast to normal activation of these lymphocytes (direct-priming) which results from presentation of endogenous antigens.
Descriptor ID |
D045142
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MeSH Number(s) |
G12.450.050.400.545.150 G12.565.150
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cross-Priming".
Below are MeSH descriptors whose meaning is more specific than "Cross-Priming".
This graph shows the total number of publications written about "Cross-Priming" by people in this website by year, and whether "Cross-Priming" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2005 | 2 | 0 | 2 |
2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2020 | 2 | 1 | 3 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cross-Priming" by people in Profiles.
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Cruz FM, Chan A, Rock KL. Pathways of MHC I cross-presentation of exogenous antigens. Semin Immunol. 2023 03; 66:101729.
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Qiu CC, Kotredes KP, Cremers T, Patel S, Afanassiev A, Slifker M, Gallucci S, Gamero AM. Targeted Stat2 deletion in conventional dendritic cells impairs CTL responses but does not affect antibody production. Oncoimmunology. 2020 12 29; 10(1):1860477.
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Riding RL, Richmond JM, Fukuda K, Harris JE. Type I interferon signaling limits viral vector priming of CD8+ T cells during initiation of vitiligo and melanoma immunotherapy. Pigment Cell Melanoma Res. 2021 07; 34(4):683-695.
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Colbert JD, Cruz FM, Rock KL. Cross-presentation of exogenous antigens on MHC I molecules. Curr Opin Immunol. 2020 06; 64:1-8.
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Cruz FM, Colbert JD, Merino E, Kriegsman BA, Rock KL. The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules. Annu Rev Immunol. 2017 04 26; 35:149-176.
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Xu J, Lee MH, Chakhtoura M, Green BL, Kotredes KP, Chain RW, Sriram U, Gamero AM, Gallucci S. STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-Presentation. J Immunol. 2016 07 01; 197(1):326-36.
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Behar SM. Antigen-specific CD8(+) T cells and protective immunity to tuberculosis. Adv Exp Med Biol. 2013; 783:141-63.
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Engelhardt JJ, Boldajipour B, Beemiller P, Pandurangi P, Sorensen C, Werb Z, Egeblad M, Krummel MF. Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells. Cancer Cell. 2012 Mar 20; 21(3):402-17.
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Rock KL, Farf?n-Arribas DJ, Shen L. Proteases in MHC class I presentation and cross-presentation. J Immunol. 2010 Jan 01; 184(1):9-15.
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Powell TJ, Strutt T, Reome J, Hollenbaugh JA, Roberts AD, Woodland DL, Swain SL, Dutton RW. Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus. J Immunol. 2007 Jan 15; 178(2):1030-8.