Nuclear Localization Signals
"Nuclear Localization Signals" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Short, predominantly basic amino acid sequences identified as nuclear import signals for some proteins. These sequences are believed to interact with specific receptors at the NUCLEAR PORE.
| Descriptor ID |
D019913
|
| MeSH Number(s) |
D12.644.770.610 G02.111.570.060.670.610
|
| Concept/Terms |
Nuclear Localization Signals- Nuclear Localization Signals
- Nuclear Localization Signal Peptide
- Nuclear Localization Signal
- Signal, Nuclear Localization
- Signals, Nuclear Localization
- NLS Peptide
- NLS Peptides
- Peptide, NLS
- Peptides, NLS
|
Below are MeSH descriptors whose meaning is more general than "Nuclear Localization Signals".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Localization Signals".
This graph shows the total number of publications written about "Nuclear Localization Signals" by people in this website by year, and whether "Nuclear Localization Signals" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Localization Signals" by people in Profiles.
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Goswami R, Gupta A, Bednova O, Coulombe G, Patel D, Rotello VM, Leyton JV. Nuclear localization signal-tagged systems: relevant nuclear import principles in the context of current therapeutic design. Chem Soc Rev. 2024 Jan 02; 53(1):204-226.
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Liu P, Luk K, Shin M, Idrizi F, Kwok S, Roscoe B, Mintzer E, Suresh S, Morrison K, Fraz?o JB, Bolukbasi MF, Ponnienselvan K, Luban J, Zhu LJ, Lawson ND, Wolfe SA. Enhanced Cas12a editing in mammalian cells and zebrafish. Nucleic Acids Res. 2019 May 07; 47(8):4169-4180.
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Ray M, Tang R, Jiang Z, Rotello VM. Quantitative tracking of protein trafficking to the nucleus using cytosolic protein delivery by nanoparticle-stabilized nanocapsules. Bioconjug Chem. 2015 Jun 17; 26(6):1004-7.
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Parelkar SS, Letteri R, Chan-Seng D, Zolochevska O, Ellis J, Figueiredo M, Emrick T. Polymer-peptide delivery platforms: effect of oligopeptide orientation on polymer-based DNA delivery. Biomacromolecules. 2014 Apr 14; 15(4):1328-36.
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Nargund AM, Pellegrino MW, Fiorese CJ, Baker BM, Haynes CM. Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation. Science. 2012 Aug 03; 337(6094):587-90.
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Regeling A, Armata HL, Gallant J, Jones SN, Sluss HK. Mice defective in p53 nuclear localization signal 1 exhibit exencephaly. Transgenic Res. 2011 Aug; 20(4):899-912.
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Gildemeister OS, Sage JM, Knight KL. Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C. J Biol Chem. 2009 Nov 13; 284(46):31945-52.
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Pande S, Ali SA, Dowdy C, Zaidi SK, Ito K, Ito Y, Montecino MA, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes. J Cell Physiol. 2009 Mar; 218(3):473-9.
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Dange T, Gr?nwald D, Gr?nwald A, Peters R, Kubitscheck U. Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study. J Cell Biol. 2008 Oct 06; 183(1):77-86.
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Javed A, Afzal F, Bae JS, Gutierrez S, Zaidi K, Pratap J, van Wijnen AJ, Stein JL, Stein GS, Lian JB. Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation. Cells Tissues Organs. 2009; 189(1-4):133-7.