Eukaryotic Initiation Factor-4G
"Eukaryotic Initiation Factor-4G" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A component of eukaryotic initiation factor-4F that is involved in multiple protein interactions at the site of translation initiation. Thus it may serve a role in bringing together various initiation factors at the site of translation initiation.
Descriptor ID |
D039603
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MeSH Number(s) |
D12.776.835.725.868.500.875
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Concept/Terms |
Eukaryotic Initiation Factor-4G- Eukaryotic Initiation Factor-4G
- Eukaryotic Initiation Factor 4G
- EIF4G
- Peptide Initiation Factor EIF-4G
- Peptide Initiation Factor EIF 4G
- Eukaryotic Translation Initiation Factor 4 gamma
- Eukaryotic-Translation Initiation Factor 4G
- Eukaryotic Translation Initiation Factor 4G
- EIF-4G
- EIF 4G
- Eukaryotic Peptide Initiation Factor-4G
- Eukaryotic Peptide Initiation Factor 4G
|
Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-4G".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-4G".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-4G" by people in this website by year, and whether "Eukaryotic Initiation Factor-4G" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-4G" by people in Profiles.
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Keane L, Antignano I, Riechers SP, Zollinger R, Dumas AA, Offermann N, Bernis ME, Russ J, Graelmann F, McCormick PN, Esser J, Tejera D, Nagano A, Wang J, Chelala C, Biederbick Y, Halle A, Salomoni P, Heneka MT, Capasso M. mTOR-dependent translation amplifies microglia priming in aging mice. J Clin Invest. 2021 01 04; 131(1).
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Hill ME, Kumar A, Wells JA, Hobman TC, Julien O, Hardy JA. The Unique Cofactor Region of Zika Virus NS2B-NS3 Protease Facilitates Cleavage of Key Host Proteins. ACS Chem Biol. 2018 09 21; 13(9):2398-2405.
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Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ? cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28.
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Xu S, Hafer N, Agunwamba B, Schedl P. The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster. PLoS Genet. 2012; 8(11):e1003079.
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Amrani N, Ghosh S, Mangus DA, Jacobson A. Translation factors promote the formation of two states of the closed-loop mRNP. Nature. 2008 Jun 26; 453(7199):1276-80.
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Kim JH, Richter JD. RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB. Genes Dev. 2007 Oct 15; 21(20):2571-9.
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Nekrasov MP, Ivshina MP, Chernov KG, Kovrigina EA, Evdokimova VM, Thomas AA, Hershey JW, Ovchinnikov LP. The mRNA-binding protein YB-1 (p50) prevents association of the eukaryotic initiation factor eIF4G with mRNA and inhibits protein synthesis at the initiation stage. J Biol Chem. 2003 Apr 18; 278(16):13936-43.