"Chagas Cardiomyopathy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Descriptor ID |
D002598
|
| MeSH Number(s) |
C03.752.300.900.200.190 C14.280.238.190
|
| Concept/Terms |
Chagas Cardiomyopathy- Chagas Cardiomyopathy
- Trypanosomiasis, Cardiovascular
- Cardiovascular Trypanosomiasis
- Chagas' Cardiomyopathy
- Cardiomyopathy, Chagas'
- Cardiomyopathy, Chagas
|
Below are MeSH descriptors whose meaning is more general than "Chagas Cardiomyopathy".
Below are MeSH descriptors whose meaning is more specific than "Chagas Cardiomyopathy".
This graph shows the total number of publications written about "Chagas Cardiomyopathy" by people in this website by year, and whether "Chagas Cardiomyopathy" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chagas Cardiomyopathy" by people in Profiles.
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do Vale INPC, Almeida GG, Rimkute I, Liechti T, de Ara?jo FF, Dos Santos LI, Henriques PM, Rocha MODC, El?i-Santos SM, Martins Filho OA, Roederer M, Sher A, Jankovic D, Teixeira Carvalho A, Antonelli LRDV. Signatures of CD4+ T and B cells are associated with distinct stages of chronic chagasic cardiomyopathy. Front Immunol. 2024; 15:1385850.
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Rodrigues da Cunha GM, Azevedo MA, Nogueira DS, Cl?maco MC, Valencia Ayala E, Jimenez Chunga JA, La Valle RJY, da Cunha Galv?o LM, Chiari E, Brito CRN, Soares RP, Nogueira PM, Fujiwara RT, Gazzinelli R, Hincapie R, Chaves CS, Oliveira FMS, Finn MG, Marques AF. a-Gal immunization positively impacts Trypanosoma cruzi colonization of heart tissue in a mouse model. PLoS Negl Trop Dis. 2021 07; 15(7):e0009613.
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Gibaldi D, Vilar-Pereira G, Pereira IR, Silva AA, Barrios LC, Ramos IP, Mata Dos Santos HA, Gazzinelli R, Lannes-Vieira J. CCL3/Macrophage Inflammatory Protein-1a Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFN?-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy. Front Immunol. 2020; 11:306.
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Pontes Ferreira C, Cariste LM, Ferri Moraschi B, Ferrarini Zanetti B, Won Han S, Araki Ribeiro D, Vieira Machado A, Lannes-Vieira J, Gazzinelli RT, Vasconcelos JRC. CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge. PLoS Negl Trop Dis. 2019 07; 13(7):e0007597.
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Pereira IR, Vilar-Pereira G, Marques V, da Silva AA, Caetano B, Moreira OC, Machado AV, Bruna-Romero O, Rodrigues MM, Gazzinelli RT, Lannes-Vieira J. A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy. PLoS Pathog. 2015 Jan; 11(1):e1004594.
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Silverio JC, Pereira IR, Cipitelli Mda C, Vinagre NF, Rodrigues MM, Gazzinelli RT, Lannes-Vieira J. CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy. PLoS Pathog. 2012; 8(4):e1002645.