Chagas Cardiomyopathy

"Chagas Cardiomyopathy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.

Descriptor ID	D002598
MeSH Number(s)	C03.752.300.900.200.190 C14.280.238.190
Concept/Terms	Chagas Cardiomyopathy Chagas Cardiomyopathy Trypanosomiasis, Cardiovascular Cardiovascular Trypanosomiasis Chagas' Cardiomyopathy Cardiomyopathy, Chagas' Cardiomyopathy, Chagas Myocarditis, Chagas Myocarditis, Chagas

Below are MeSH descriptors whose meaning is more general than "Chagas Cardiomyopathy".

Diseases [C]
Parasitic Diseases [C03]
Protozoan Infections [C03.752]
Euglenozoa Infections [C03.752.300]
Trypanosomiasis [C03.752.300.900]
Chagas Disease [C03.752.300.900.200]
Chagas Cardiomyopathy [C03.752.300.900.200.190]
Cardiovascular Diseases [C14]
Heart Diseases [C14.280]
Cardiomyopathies [C14.280.238]
Chagas Cardiomyopathy [C14.280.238.190]

Below are MeSH descriptors whose meaning is related to "Chagas Cardiomyopathy".

Below are MeSH descriptors whose meaning is more specific than "Chagas Cardiomyopathy".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chagas Cardiomyopathy" by people in this website by year, and whether "Chagas Cardiomyopathy" was a major or minor topic of these publications.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 2012 and 2015 and 2016 and 2019 and 2020 and 2021 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Total
2012	1	1
2015	1	1
2016	1	1
2019	1	1
2020	1	1
2021	1	1
2024	1	1

Below are the most recent publications written about "Chagas Cardiomyopathy" by people in Profiles.

do Vale INPC, Almeida GG, Rimkute I, Liechti T, de Ara?jo FF, Dos Santos LI, Henriques PM, Rocha MODC, El?i-Santos SM, Martins Filho OA, Roederer M, Sher A, Jankovic D, Teixeira Carvalho A, Antonelli LRDV. Signatures of CD4+ T and B cells are associated with distinct stages of chronic chagasic cardiomyopathy. Front Immunol. 2024; 15:1385850.

View in: PubMed
Rodrigues da Cunha GM, Azevedo MA, Nogueira DS, Cl?maco MC, Valencia Ayala E, Jimenez Chunga JA, La Valle RJY, da Cunha Galv?o LM, Chiari E, Brito CRN, Soares RP, Nogueira PM, Fujiwara RT, Gazzinelli R, Hincapie R, Chaves CS, Oliveira FMS, Finn MG, Marques AF. a-Gal immunization positively impacts Trypanosoma cruzi colonization of heart tissue in a mouse model. PLoS Negl Trop Dis. 2021 07; 15(7):e0009613.

View in: PubMed
Gibaldi D, Vilar-Pereira G, Pereira IR, Silva AA, Barrios LC, Ramos IP, Mata Dos Santos HA, Gazzinelli R, Lannes-Vieira J. CCL3/Macrophage Inflammatory Protein-1a Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFN?-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy. Front Immunol. 2020; 11:306.

View in: PubMed
Pontes Ferreira C, Cariste LM, Ferri Moraschi B, Ferrarini Zanetti B, Won Han S, Araki Ribeiro D, Vieira Machado A, Lannes-Vieira J, Gazzinelli RT, Vasconcelos JRC. CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge. PLoS Negl Trop Dis. 2019 07; 13(7):e0007597.

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Passos LS, Villani FN, Magalh?es LM, Gollob KJ, Antonelli LR, Nunes MC, Dutra WO. Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease. J Infect Dis. 2016 09 15; 214(6):935-44.

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Pereira IR, Vilar-Pereira G, Marques V, da Silva AA, Caetano B, Moreira OC, Machado AV, Bruna-Romero O, Rodrigues MM, Gazzinelli RT, Lannes-Vieira J. A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy. PLoS Pathog. 2015 Jan; 11(1):e1004594.

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Silverio JC, Pereira IR, Cipitelli Mda C, Vinagre NF, Rodrigues MM, Gazzinelli RT, Lannes-Vieira J. CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy. PLoS Pathog. 2012; 8(4):e1002645.

View in: PubMed

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