"Herpesvirus 6, Human" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of the ROSEOLOVIRUS genus of the Betaherpesvirales subfamily isolated from patients with AIDS and other LYMPHOPROLIFERATIVE DISORDERS. It infects and replicates in fresh and established lines of hematopoietic cells and cells of neural origin. It also appears to alter the activity of NK CELLS. HHV-6; (HBLV) antibodies are elevated in patients with AIDS; SJOGREN'S SYNDROME; SARCOIDOSIS; CHRONIC FATIGUE SYNDROME, and certain malignancies. HHV-6A is the most common cause of EXANTHEMA SUBITUM and has been implicated in encephalitis. When HHV-6 integrates into the host genome it is referred to as ciHVH-6. When such VIRUS INTEGRATION occurs into the germline it is referred to as iciHHV-6.
Descriptor ID |
D015654
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MeSH Number(s) |
B04.280.382.150.750.400
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Concept/Terms |
Herpesvirus 6, Human- Herpesvirus 6, Human
- HHV-6
- Human betaherpesvirus 6
- Human betaherpesvirus 6s
- HHV6
- Human Herpesvirus 6
- HBLV
- Human B-Lymphotropic Virus
- B-Lymphotropic Virus, Human
- B-Lymphotropic Viruses, Human
- Human B Lymphotropic Virus
- Human B-Lymphotropic Viruses
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Below are MeSH descriptors whose meaning is more general than "Herpesvirus 6, Human".
Below are MeSH descriptors whose meaning is more specific than "Herpesvirus 6, Human".
This graph shows the total number of publications written about "Herpesvirus 6, Human" by people in this website by year, and whether "Herpesvirus 6, Human" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2018 | 2 | 0 | 2 |
2019 | 2 | 0 | 2 |
2020 | 0 | 1 | 1 |
2022 | 2 | 0 | 2 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Herpesvirus 6, Human" by people in Profiles.
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Weaver GC, Schneider CL, Becerra-Artiles A, Clayton KL, Hudson AW, Stern LJ. The HHV-6B U20 glycoprotein binds ULBP1, masking it from recognition by NKG2D and interfering with natural killer cell activation. Front Immunol. 2024; 15:1363156.
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Weaver GC, Arya R, Schneider CL, Hudson AW, Stern LJ. Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7. Front Immunol. 2022; 13:864898.
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Deshpande A, Herrmann Z, Hsu J, Rush AJ. HHV-6 and Schizophrenia: An Unusual Presentation or an Unproven Etiology? Prim Care Companion CNS Disord. 2022 Jan 06; 24(1).
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Itzhaki RF, Golde TE, Heneka MT, Readhead B. Do infections have a role in the pathogenesis of Alzheimer disease? Nat Rev Neurol. 2020 04; 16(4):193-197.
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Eliassen E, Hemond CC, Santoro JD. HHV-6-Associated Neurological Disease in Children: Epidemiologic, Clinical, Diagnostic, and Treatment Considerations. Pediatr Neurol. 2020 04; 105:10-20.
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Becerra-Artiles A, Cruz J, Leszyk JD, Sidney J, Sette A, Shaffer SA, Stern LJ. Naturally processed HLA-DR3-restricted HHV-6B peptides are recognized broadly with polyfunctional and cytotoxic CD4 T-cell responses. Eur J Immunol. 2019 08; 49(8):1167-1185.
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Santoro JD, Hemond CC. Human herpesvirus 6 associated post-transplant acute limbic encephalitis: Clinical observations of biomarkers for risk of seizure in a pediatric population. Transpl Infect Dis. 2019 Feb; 21(1):e13003.
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Becerra-Artiles A, Santoro T, Stern LJ. Evaluation of a method to measure HHV-6B infection in?vitro based on cell size. Virol J. 2018 01 05; 15(1):4.
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Becerra-Artiles A, Dominguez-Amorocho O, Stern LJ, Calvo-Calle JM. A Simple Proteomics-Based Approach to Identification of Immunodominant Antigens from a Complex Pathogen: Application to the CD4 T Cell Response against Human Herpesvirus 6B. PLoS One. 2015; 10(11):e0142871.
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Becerra A, Gibson L, Stern LJ, Calvo-Calle JM. Immune response to HHV-6 and implications for immunotherapy. Curr Opin Virol. 2014 Dec; 9:154-61.