Insulin-Like Growth Factor Binding Protein 1
"Insulin-Like Growth Factor Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
| Descriptor ID |
D018970
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| MeSH Number(s) |
D12.776.157.420.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 1".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in this website by year, and whether "Insulin-Like Growth Factor Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in Profiles.
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Young CH, Snow B, DeVore SB, Mohandass A, Nemmara VV, Thompson PR, Thyagarajan B, Navratil AM, Cherrington BD. Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells. Reproduction. 2021 07 08; 162(2):117-127.
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Young CH, Rothfuss HM, Gard PF, Muth A, Thompson PR, Ashley RL, Cherrington BD. Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells. Reproduction. 2017 01; 153(1):1-10.
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Messmer-Blust AF, Philbrick MJ, Guo S, Wu J, He P, Guo S, Li J. RTEF-1 attenuates blood glucose levels by regulating insulin-like growth factor binding protein-1 in the endothelium. Circ Res. 2012 Sep 28; 111(8):991-1001.
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Boney CM, Moats-Staats BM, Stiles AD, D'Ercole AJ. Expression of insulin-like growth factor-I (IGF-I) and IGF-binding proteins during adipogenesis. Endocrinology. 1994 Nov; 135(5):1863-8.
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D'Ercole AJ, Dai Z, Xing Y, Boney C, Wilkie MB, Lauder JM, Han VK, Clemmons DR. Brain growth retardation due to the expression of human insulin like growth factor binding protein-1 in transgenic mice: an in vivo model for the analysis of igf function in the brain. Brain Res Dev Brain Res. 1994 Oct 14; 82(1-2):213-22.
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Dai Z, Xing Y, Boney CM, Clemmons DR, D'Ercole AJ. Human insulin-like growth factor-binding protein-1 (hIGFBP-1) in transgenic mice: characterization and insights into the regulation of IGFBP-1 expression. Endocrinology. 1994 Oct; 135(4):1316-27.