"Amphetamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
| Descriptor ID |
D000661
|
| MeSH Number(s) |
D02.092.471.683.152.110
|
| Concept/Terms |
Amphetamine- Amphetamine
- Amfetamine
- Phenopromin
- Desoxynorephedrin
- Phenamine
l-Amphetamine- l-Amphetamine
- l Amphetamine
- levo-Amphetamine
- levo Amphetamine
- Levoamphetamine
|
Below are MeSH descriptors whose meaning is more general than "Amphetamine".
Below are MeSH descriptors whose meaning is more specific than "Amphetamine".
This graph shows the total number of publications written about "Amphetamine" by people in this website by year, and whether "Amphetamine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Amphetamine" by people in Profiles.
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Fagan RR, Kearney PJ, Luethi D, Bolden NC, Sitte HH, Emery P, Melikian HE. Dopaminergic Ric GTPase activity impacts amphetamine sensitivity and sleep quality in a dopamine transporter-dependent manner in Drosophila melanogaster. Mol Psychiatry. 2021 12; 26(12):7793-7802.
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Marimuthu SP, Iyer G, Segal JB, Singh S. Patient-relevant outcomes associated with generic tamsulosin, levothyroxine and amphetamine in the FDA Adverse Event Reporting System: a pilot study. J Comp Eff Res. 2017 Jul; 6(5):437-447.
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Pang X, Hogan EM, Casserly A, Gao G, Gardner PD, Tapper AR. Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival. Mol Cell Neurosci. 2014 Jan; 58:22-8.
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Soll LG, Grady SR, Salminen O, Marks MJ, Tapper AR. A role for a4(non-a6)* nicotinic acetylcholine receptors in motor behavior. Neuropharmacology. 2013 Oct; 73:19-30.
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Due?as-Garcia OF. False-positive amphetamine toxicology screen results in three pregnant women using labetalol. Obstet Gynecol. 2011 Aug; 118(2 Pt 1):360-361.
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Laganiere J, Kells AP, Lai JT, Guschin D, Paschon DE, Meng X, Fong LK, Yu Q, Rebar EJ, Gregory PD, Bankiewicz KS, Forsayeth J, Zhang HS. An engineered zinc finger protein activator of the endogenous glial cell line-derived neurotrophic factor gene provides functional neuroprotection in a rat model of Parkinson's disease. J Neurosci. 2010 Dec 08; 30(49):16469-74.
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Abdallah L, Bonasera SJ, Hopf FW, O'Dell L, Giorgetti M, Jongsma M, Carra S, Pierucci M, Di Giovanni G, Esposito E, Parsons LH, Bonci A, Tecott LH. Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. J Neurosci. 2009 Jun 24; 29(25):8156-65.
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Boudanova E, Navaroli DM, Melikian HE. Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent. Neuropharmacology. 2008 Mar; 54(3):605-12.
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Zhang J, Pho V, Bonasera SJ, Holtzman J, Tang AT, Hellmuth J, Tang S, Janak PH, Tecott LH, Huang EJ. Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nat Neurosci. 2007 Jan; 10(1):77-86.
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Fadel J, Dobner PR, Deutch AY. Amphetamine-elicited striatal Fos expression is attenuated in neurotensin null mutant mice. Neurosci Lett. 2006 Jul 10; 402(1-2):97-101.