SOX9 Transcription Factor

"SOX9 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A SOXE transcription factor that plays a critical role in regulating CHONDROGENESIS; OSTEOGENESIS; and male sex determination. Loss of function of the SOX9 transcription factor due to genetic mutations is a cause of CAMPOMELIC DYSPLASIA.

Descriptor ID	D055758
MeSH Number(s)	D12.776.260.719.500.500 D12.776.660.235.400.750.500.500 D12.776.664.235.400.750.500.500 D12.776.930.823.500.500
Concept/Terms	SOX9 Transcription Factor SOX9 Transcription Factor Transcription Factor, SOX9 SOX-9 Transcription Factor SOX 9 Transcription Factor Transcription Factor, SOX-9

Below are MeSH descriptors whose meaning is more general than "SOX9 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
SOX Transcription Factors [D12.776.260.719]
SOXE Transcription Factors [D12.776.260.719.500]
SOX9 Transcription Factor [D12.776.260.719.500.500]
Nuclear Proteins [D12.776.660]
Chromosomal Proteins, Non-Histone [D12.776.660.235]
High Mobility Group Proteins [D12.776.660.235.400]
SOX Transcription Factors [D12.776.660.235.400.750]
SOXE Transcription Factors [D12.776.660.235.400.750.500]
SOX9 Transcription Factor [D12.776.660.235.400.750.500.500]
Nucleoproteins [D12.776.664]
Chromosomal Proteins, Non-Histone [D12.776.664.235]
High Mobility Group Proteins [D12.776.664.235.400]
SOX Transcription Factors [D12.776.664.235.400.750]
SOXE Transcription Factors [D12.776.664.235.400.750.500]
SOX9 Transcription Factor [D12.776.664.235.400.750.500.500]
Transcription Factors [D12.776.930]
SOX Transcription Factors [D12.776.930.823]
SOXE Transcription Factors [D12.776.930.823.500]
SOX9 Transcription Factor [D12.776.930.823.500.500]

Below are MeSH descriptors whose meaning is related to "SOX9 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "SOX9 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "SOX9 Transcription Factor" by people in this website by year, and whether "SOX9 Transcription Factor" was a major or minor topic of these publications.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2006	0	1	1
2008	0	1	1
2013	1	0	1
2014	0	1	1
2016	1	0	1
2018	1	1	2
2024	0	1	1

Below are the most recent publications written about "SOX9 Transcription Factor" by people in Profiles.

Han D, Labaf M, Zhao Y, Owiredu J, Zhang S, Patel K, Venkataramani K, Steinfeld JS, Han W, Li M, Liu M, Wang Z, Besschetnova A, Patalano S, Mulhearn MJ, Macoska JA, Yuan X, Balk SP, Nelson PS, Plymate SR, Gao S, Siegfried KR, Liu R, Stangis MM, Foxa G, Czernik PJ, Williams BO, Zarringhalam K, Li X, Cai C. Androgen receptor splice variants drive castration-resistant prostate cancer metastasis by activating distinct transcriptional programs. J Clin Invest. 2024 Apr 30; 134(11).

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Palaria A, Angelo JR, Guertin TM, Mager J, Tremblay KD. Patterning of the hepato-pancreatobiliary boundary by BMP reveals heterogeneity within the murine liver bud. Hepatology. 2018 07; 68(1):274-288.

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Das KK, Heeg S, Pitarresi JR, Reichert M, Bakir B, Takano S, Kopp JL, Wahl-Feuerstein A, Hicks P, Sander M, Rustgi AK. ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis. Dev Dyn. 2018 06; 247(6):854-866.

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Ma F, Ye H, He HH, Gerrin SJ, Chen S, Tanenbaum BA, Cai C, Sowalsky AG, He L, Wang H, Balk SP, Yuan X. SOX9 drives WNT pathway activation in prostate cancer. J Clin Invest. 2016 05 02; 126(5):1745-58.

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Liu H, Zhu S, Zhang C, Lu P, Hu J, Yin Z, Ma Y, Chen X, OuYang H. Crucial transcription factors in tendon development and differentiation: their potential for tendon regeneration. Cell Tissue Res. 2014 May; 356(2):287-98.

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Cai C, Wang H, He HH, Chen S, He L, Ma F, Mucci L, Wang Q, Fiore C, Sowalsky AG, Loda M, Liu XS, Brown M, Balk SP, Yuan X. ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer. J Clin Invest. 2013 Mar; 123(3):1109-22.

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Ochiai T, Shibukawa Y, Nagayama M, Mundy C, Yasuda T, Okabe T, Shimono K, Kanyama M, Hasegawa H, Maeda Y, Lanske B, Pacifici M, Koyama E. Indian hedgehog roles in post-natal TMJ development and organization. J Dent Res. 2010 Apr; 89(4):349-54.

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Siegfried KR, N?sslein-Volhard C. Germ line control of female sex determination in zebrafish. Dev Biol. 2008 Dec 15; 324(2):277-87.

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Wang H, Leav I, Ibaragi S, Wegner M, Hu GF, Lu ML, Balk SP, Yuan X. SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res. 2008 Mar 15; 68(6):1625-30.

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Zuscik MJ, Ma L, Buckley T, Puzas JE, Drissi H, Schwarz EM, O'Keefe RJ. Lead induces chondrogenesis and alters transforming growth factor-beta and bone morphogenetic protein signaling in mesenchymal cell populations. Environ Health Perspect. 2007 Sep; 115(9):1276-82.

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