Lysergic Acid Diethylamide
"Lysergic Acid Diethylamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
Descriptor ID |
D008238
|
MeSH Number(s) |
D03.132.327.287.572.522 D03.633.400.439.572.522
|
Concept/Terms |
Lysergic Acid Diethylamide- Lysergic Acid Diethylamide
- Acid Diethylamide, Lysergic
- Diethylamide, Lysergic Acid
- Lysergide
- LSD
- LSD-25
- LSD 25
|
Below are MeSH descriptors whose meaning is more general than "Lysergic Acid Diethylamide".
Below are MeSH descriptors whose meaning is more specific than "Lysergic Acid Diethylamide".
This graph shows the total number of publications written about "Lysergic Acid Diethylamide" by people in this website by year, and whether "Lysergic Acid Diethylamide" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lysergic Acid Diethylamide" by people in Profiles.
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McLean TH, Chambers JJ, Parrish JC, Braden MR, Marona-Lewicka D, Kurrasch-Orbaugh D, Nichols DE. C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor. J Med Chem. 2006 Jul 13; 49(14):4269-74.
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Chambers JJ, Parrish JC, Jensen NH, Kurrasch-Orbaugh DM, Marona-Lewicka D, Nichols DE. Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands. J Med Chem. 2003 Jul 31; 46(16):3526-35.