Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.
De Palma M, Mazzieri R, Politi LS, Pucci F, Zonari E, Sitia G, Mazzoleni S, Moi D, Venneri MA, Indraccolo S, Falini A, Guidotti LG, Galli R, Naldini L. Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer Cell. 2008 Oct 07; 14(4):299-311.
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Animals
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Cell Line, Tumor
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Cell Proliferation
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Cells, Cultured
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Female
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Genetic Therapy
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Glioma
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Hematopoiesis
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Hematopoietic Stem Cell Transplantation
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Hematopoietic Stem Cells
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Humans
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Immunity, Innate
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Interferon-alpha
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Mammary Neoplasms, Experimental
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Mice
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Mice, Nude
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Mice, Transgenic
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Monocytes
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Neoplasm Metastasis
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Neovascularization, Pathologic
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Promoter Regions, Genetic
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Receptor, TIE-2
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Recombinant Fusion Proteins
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Time Factors
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Transduction, Genetic
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Wound Healing