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An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense.
NHR-49/PPAR-a and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase.
TFEB-driven lysosomal biogenesis is pivotal for PGC1?a??-dependent renal stress resistance.
Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo.
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An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense.
Najibi M, Labed SA, Visvikis O, Irazoqui JE. An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense. Cell Rep. 2016 05 24; 15(8):1728-42.
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PubMed
subject areas
Animals
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Enzyme Activation
Evolution, Molecular
Host-Pathogen Interactions
Macrophages
Mice
Microbial Viability
Protein Kinase C
Protein Kinase C-alpha
RAW 264.7 Cells
Salmonella enterica
Signal Transduction
Staphylococcal Infections
Staphylococcus aureus
Type C Phospholipases
authors with profiles
Javier Elbio Irazoqui PhD