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Multicenter phase I trial of the mitogen-activated protein kinase 1/2 inhibitor BAY 86-9766 in patients with advanced cancer.
CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice.
CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young mice.
G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates.
CpG DNA is an effective oral adjuvant to protein antigens in mice.
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CpG DNA is an effective oral adjuvant to protein antigens in mice.
McCluskie MJ, Weeratna RD, Krieg AM, Davis HL. CpG DNA is an effective oral adjuvant to protein antigens in mice. Vaccine. 2000 Nov 22; 19(7-8):950-7.
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PubMed
subject areas
Adjuvants, Immunologic
Administration, Oral
Animals
Antigens
Base Sequence
CpG Islands
Female
Hepatitis B Surface Antigens
Immunity, Mucosal
Immunoglobulin G
In Vitro Techniques
Lymphocyte Activation
Mice
Mice, Inbred BALB C
Oligodeoxyribonucleotides
Tetanus Toxoid
T-Lymphocytes
T-Lymphocytes, Cytotoxic
Vaccines, DNA
authors with profiles
Arthur M Krieg MD