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A first-in-man phase i and pharmacokinetic study on CHR-2797 (Tosedostat), an inhibitor of M1 aminopeptidases, in patients with advanced solid tumors.
BRAF/KRAS gene sequencing of sebaceous neoplasms after mismatch repair protein analysis.
Mode of action: developmental thyroid hormone insufficiency--neurological abnormalities resulting from exposure to propylthiouracil.
Sanjay, Brinda
Igniting the firestorm: The inflammasome in autoinflammatory syndromes.
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Igniting the firestorm: The inflammasome in autoinflammatory syndromes.
Humphries F, Fitzgerald KA. Igniting the firestorm: The inflammasome in autoinflammatory syndromes. J Allergy Clin Immunol. 2021 12; 148(6):1470-1472.
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PubMed
subject areas
Animals
Autoimmune Diseases
Humans
Inflammasomes
Interleukin-18
Interleukin-1beta
Mutation
Neutrophils
NLR Family, Pyrin Domain-Containing 3 Protein
Pyroptosis
authors with profiles
Fiachra Emanuel Humphries PhD
Katherine A Fitzgerald PhD