"Ataxin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chromatin-binding factor that represses Notch signaling and associates with RNA. Expansion of the polyglutamine tract by expanded CAG repeats in the ATXN1 gene coding region is associated with SPINOCEREBELLAR ATAXIA 1.
| Descriptor ID |
D000067696
|
| MeSH Number(s) |
D12.776.631.069.500 D12.776.660.075.500
|
| Concept/Terms |
Ataxin-1- Ataxin-1
- Ataxin 1
- SCA1 Protein
- Protein, SCA1
- Atxn-1 Protein
- Atxn 1 Protein
- Protein, Atxn-1
- Atxn1 Protein
- Protein, Atxn1
- Spinocerebellar Ataxia Type 1 Protein
- Ataxin-1 Protein
- Ataxin 1 Protein
- Protein, Ataxin-1
|
Below are MeSH descriptors whose meaning is more general than "Ataxin-1".
Below are MeSH descriptors whose meaning is more specific than "Ataxin-1".
This graph shows the total number of publications written about "Ataxin-1" by people in this website by year, and whether "Ataxin-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ataxin-1" by people in Profiles.
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March ZM, King OD, Shorter J. Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative disease. Brain Res. 2016 09 15; 1647:9-18.
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Tang R, Noh HJ, Wang D, Sigurdsson S, Swofford R, Perloski M, Duxbury M, Patterson EE, Albright J, Castelhano M, Auton A, Boyko AR, Feng G, Lindblad-Toh K, Karlsson EK. Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder. Genome Biol. 2014 Mar 14; 15(3):R25.
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Colvin GA, Lambert JF, Dooner MS, Cerny J, Quesenberry PJ. Murine allogeneic in vivo stem cell homing(,). J Cell Physiol. 2007 May; 211(2):386-91.
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Xia H, Mao Q, Eliason SL, Harper SQ, Martins IH, Orr HT, Paulson HL, Yang L, Kotin RM, Davidson BL. RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nat Med. 2004 Aug; 10(8):816-20.