"DNA Ligase ATP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent.
Descriptor ID |
D000072481
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MeSH Number(s) |
D08.811.074.500.500 D08.811.464.754.600.500
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Concept/Terms |
DNA Ligase ATP- DNA Ligase ATP
- ATP, DNA Ligase
- Ligase ATP, DNA
- Polydeoxyribonucleotide Synthase ATP
- ATP, Polydeoxyribonucleotide Synthase
- Synthase ATP, Polydeoxyribonucleotide
- DNA Ligases, ATP-Dependent
- ATP-Dependent DNA Ligases
- DNA Ligases, ATP Dependent
- Ligases, ATP-Dependent DNA
DNA Ligase IIIalpha- DNA Ligase IIIalpha
- IIIalpha, DNA Ligase
- Ligase IIIalpha, DNA
- LIGIIIalpha Protein
DNA Ligase III- DNA Ligase III
- Ligase III, DNA
- DNA Ligase II
- Ligase II, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Ligase ATP".
Below are MeSH descriptors whose meaning is more specific than "DNA Ligase ATP".
This graph shows the total number of publications written about "DNA Ligase ATP" by people in this website by year, and whether "DNA Ligase ATP" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Ligase ATP" by people in Profiles.
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Paes Dias M, Tripathi V, van der Heijden I, Cong K, Manolika EM, Bhin J, Gogola E, Galanos P, Annunziato S, Lieftink C, And?jar-S?nchez M, Chakrabarty S, Smith GCM, van de Ven M, Beijersbergen RL, Bartkova J, Rottenberg S, Cantor S, Bartek J, Ray Chaudhuri A, Jonkers J. Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps. Mol Cell. 2021 11 18; 81(22):4692-4708.e9.