Cholesterol 24-Hydroxylase
"Cholesterol 24-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A steroid hydroxylase that functions in CHOLESTEROL homeostasis in the brain. It converts cholesterol into 24S-hydroxycholesterol, which is transported over the BLOOD-BRAIN BARRIER more rapidly than unmetabolized cholesterol.
| Descriptor ID |
D000072556
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| MeSH Number(s) |
D08.244.453.875.500 D08.244.453.915.025 D08.811.682.690.708.170.497.500 D08.811.682.690.708.170.915.025 D12.776.422.220.453.875.500 D12.776.422.220.453.915.025
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| Concept/Terms |
Cholesterol 24-Hydroxylase- Cholesterol 24-Hydroxylase
- Cholesterol 24 Hydroxylase
- Brain-Specific 24S-Hydroxylase
- Brain Specific 24S Hydroxylase
Cholestane Tetrol 24-Hydroxylase- Cholestane Tetrol 24-Hydroxylase
- Cholestane Tetrol 24 Hydroxylase
- 5(beta)-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol-24S-hydroxylase
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Below are MeSH descriptors whose meaning is more general than "Cholesterol 24-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Cholesterol 24-Hydroxylase".
This graph shows the total number of publications written about "Cholesterol 24-Hydroxylase" by people in this website by year, and whether "Cholesterol 24-Hydroxylase" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cholesterol 24-Hydroxylase" by people in Profiles.
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N?brega C, Concei??o A, Costa RG, Koppenol R, Sequeira RL, Nunes R, Carmo-Silva S, Marcelo A, Matos CA, Betuing S, Caboche J, Cartier N, Alves S. The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease. BMC Res Notes. 2020 Apr 10; 13(1):210.
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Burlot MA, Braudeau J, Michaelsen-Preusse K, Potier B, Ayciriex S, Varin J, Gautier B, Djelti F, Audrain M, Dauphinot L, Fernandez-Gomez FJ, Caillierez R, Lapr?vote O, Bi?che I, Auzeil N, Potier MC, Dutar P, Korte M, Bu?e L, Blum D, Cartier N. Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology. Hum Mol Genet. 2015 Nov 01; 24(21):5965-76.
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Djelti F, Braudeau J, Hudry E, Dhenain M, Varin J, Bi?che I, Marquer C, Chali F, Ayciriex S, Auzeil N, Alves S, Langui D, Potier MC, Laprevote O, Vidaud M, Duyckaerts C, Miles R, Aubourg P, Cartier N. CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease. Brain. 2015 Aug; 138(Pt 8):2383-98.