"Click Chemistry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic chemistry methodology that mimics the modular nature of various biosynthetic processes. It uses highly reliable and selective reactions designed to "click" i.e., rapidly join small modular units together in high yield, without offensive byproducts. In combination with COMBINATORIAL CHEMISTRY TECHNIQUES, it is used for the synthesis of new compounds and combinatorial libraries.
Descriptor ID |
D057930
|
MeSH Number(s) |
E05.197.124 J01.897.836.249.124
|
Concept/Terms |
Click Chemistry- Click Chemistry
- Chemistries, Click
- Chemistry, Click
- Click Chemistries
- Click Chemical Techniques
- Chemical Technique, Click
- Chemical Techniques, Click
- Click Chemical Technique
- Technique, Click Chemical
- Techniques, Click Chemical
Click Chemical Reactions- Click Chemical Reactions
- Chemical Reaction, Click
- Chemical Reactions, Click
- Click Chemical Reaction
- Reaction, Click Chemical
- Reactions, Click Chemical
|
Below are MeSH descriptors whose meaning is more general than "Click Chemistry".
Below are MeSH descriptors whose meaning is more specific than "Click Chemistry".
This graph shows the total number of publications written about "Click Chemistry" by people in this website by year, and whether "Click Chemistry" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 1 | 0 | 1 |
2018 | 0 | 1 | 1 |
2020 | 2 | 0 | 2 |
2021 | 1 | 1 | 2 |
2024 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Click Chemistry" by people in Profiles.
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Sun XL, Xue H, Gu XY, Li DS, Xiao H, Wan WM. Clickable Polymerization-Induced Emission Luminogens Toward Color-Tunable Modification of Non-Traditional Intrinsic Luminescent Polymers. Macromol Rapid Commun. 2024 Jun; 45(11):e2400045.
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van Hest J, Zheng G, Rotello VM. Bioorthogonal Chemistry and Bioconjugation: Synergistic Tools for Biology and Biomedicine. Bioconjug Chem. 2021 08 18; 32(8):1409-1410.
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Gao R, Yu CJ, Gao L, Piatkevich KD, Neve RL, Munro JB, Upadhyayula S, Boyden ES. A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy. Nat Nanotechnol. 2021 06; 16(6):698-707.
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Liu B, Wu R, Gong S, Xiao H, Thayumanavan S. In Situ Formation of Polymeric Nanoassemblies Using an Efficient Reversible Click Reaction. Angew Chem Int Ed Engl. 2020 08 24; 59(35):15135-15140.
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Kavunja HW, Biegas KJ, Banahene N, Stewart JA, Piligian BF, Groenevelt JM, Sein CE, Morita YS, Niederweis M, Siegrist MS, Swarts BM. Photoactivatable Glycolipid Probes for Identifying Mycolate-Protein Interactions in Live Mycobacteria. J Am Chem Soc. 2020 04 29; 142(17):7725-7731.
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Nemmara VV, Subramanian V, Muth A, Mondal S, Salinger AJ, Maurais AJ, Tilvawala R, Weerapana E, Thompson PR. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). ACS Chem Biol. 2018 03 16; 13(3):712-722.
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Xu J, Filion TM, Prifti F, Song J. Cytocompatible poly(ethylene glycol)-co-polycarbonate hydrogels cross-linked by copper-free, strain-promoted click chemistry. Chem Asian J. 2011 Oct 04; 6(10):2730-7.