Combinatorial Chemistry Techniques
"Combinatorial Chemistry Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technology, in which sets of reactions for solution or solid-phase synthesis, is used to create molecular libraries for analysis of compounds on a large scale.
Descriptor ID |
D020650
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MeSH Number(s) |
E05.197.312 J01.897.836.249.249
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Concept/Terms |
Combinatorial Chemistry Techniques- Combinatorial Chemistry Techniques
- Techniques, Combinatorial Chemistry
- Chemistry Technique, Combinatorial
- Combinatorial Chemistry Technique
- Technics, Combinatorial Chemistry
- Chemistry Technic, Combinatorial
- Chemistry Technics, Combinatorial
- Combinatorial Chemistry Technic
- Combinatorial Chemistry Technics
- Technic, Combinatorial Chemistry
- Chemistry Techniques, Combinatorial
- Technique, Combinatorial Chemistry
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Below are MeSH descriptors whose meaning is more general than "Combinatorial Chemistry Techniques".
Below are MeSH descriptors whose meaning is more specific than "Combinatorial Chemistry Techniques".
This graph shows the total number of publications written about "Combinatorial Chemistry Techniques" by people in this website by year, and whether "Combinatorial Chemistry Techniques" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2007 | 0 | 2 | 2 |
2008 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Combinatorial Chemistry Techniques" by people in Profiles.
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van Hest J, Zheng G, Rotello VM. Bioorthogonal Chemistry and Bioconjugation: Synergistic Tools for Biology and Biomedicine. Bioconjug Chem. 2021 08 18; 32(8):1409-1410.
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Frye EC, O'Connor CJ, Twigg DG, Elbert B, Laraia L, Hulcoop DG, Venkitaraman AR, Spring DR. Palladium-catalysed cross-coupling of vinyldisiloxanes with benzylic and allylic halides and sulfonates. Chemistry. 2012 Jul 09; 18(28):8774-9.
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Bicker KL, Sun J, Lavigne JJ, Thompson PR. Boronic acid functionalized peptidyl synthetic lectins: combinatorial library design, peptide sequencing, and selective glycoprotein recognition. ACS Comb Sci. 2011 May 09; 13(3):232-43.
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Shaw SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A, Schreiber SL. Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2):492-7.
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Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM, Lipton MA. Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB. Bioorg Med Chem. 2009 Feb 01; 17(3):1044-54.
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Knuckley B, Luo Y, Thompson PR. Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors. Bioorg Med Chem. 2008 Jan 15; 16(2):739-45.
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Abzalimov RR, Dubin PL, Kaltashov IA. Glycosaminoglycans as naturally occurring combinatorial libraries: developing a mass spectrometry-based strategy for characterization of anti-thrombin interaction with low molecular weight heparin and heparin oligomers. Anal Chem. 2007 Aug 15; 79(16):6055-63.
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Lin JM, Weng Z. Systematic detection of statistically overrepresented DNA motif association rules. Genome Inform. 2006; 17(1):124-33.
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Lee HK, Cao H, Rana TM. Design, microwave-assisted synthesis, and photophysical properties of small molecule organic antennas for luminescence resonance energy transfer. J Comb Chem. 2005 Mar-Apr; 7(2):279-84.
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Wang XG, Kidder JM, Scagliotti JP, Klempner MS, Noring R, Hu LT. Analysis of differences in the functional properties of the substrate binding proteins of the Borrelia burgdorferi oligopeptide permease (Opp) operon. J Bacteriol. 2004 Jan; 186(1):51-60.