"Reverse Genetics" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The use of techniques that produce a functional MUTATION or an effect on GENE EXPRESSION of a specific gene of interest in order to identify the role or activity of the gene product of that gene.
| Descriptor ID |
D059386
|
| MeSH Number(s) |
E05.393.731
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Reverse Genetics".
Below are MeSH descriptors whose meaning is more specific than "Reverse Genetics".
This graph shows the total number of publications written about "Reverse Genetics" by people in this website by year, and whether "Reverse Genetics" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Reverse Genetics" by people in Profiles.
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Kim K, Dauphin A, Komurlu S, McCauley SM, Yurkovetskiy L, Carbone C, Diehl WE, Strambio-De-Castillia C, Campbell EM, Luban J. Cyclophilin A protects HIV-1 from restriction by human TRIM5a. Nat Microbiol. 2019 12; 4(12):2044-2051.
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Prachanronarong KL, Canale AS, Liu P, Somasundaran M, Hou S, Poh YP, Han T, Zhu Q, Renzette N, Zeldovich KB, Kowalik TF, Kurt-Yilmaz N, Jensen JD, Bolon DNA, Marasco WA, Finberg RW, Schiffer CA, Wang JP. Mutations in Influenza A Virus Neuraminidase and Hemagglutinin Confer Resistance against a Broadly Neutralizing Hemagglutinin Stem Antibody. J Virol. 2019 01 15; 93(2).
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Grzesik P, Ko N, Oldfield LM, Vashee S, Desai PJ. Rapid and efficient in vitro excision of BAC sequences from herpesvirus genomes using Cre-mediated recombination. J Virol Methods. 2018 11; 261:67-70.
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Lawson ND. Reverse Genetics in Zebrafish: Mutants, Morphants, and Moving Forward. Trends Cell Biol. 2016 Feb; 26(2):77-79.