Pragmatic Clinical Trials as Topic

"Pragmatic Clinical Trials as Topic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Works about randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and impacts.

Descriptor ID	D064792
MeSH Number(s)	E05.318.760.250.500.365.500.500 N05.715.360.775.088.500.387.500.750 N06.850.520.450.250.250.365.500.750
Concept/Terms	Pragmatic Clinical Trials as Topic Pragmatic Clinical Trials as Topic Real World Clinical Trials Naturalistic Randomized Clinical Trial Pragmatic Trials Trials, Pragmatic Pragmatic Clinical Trials Clinical Trials, Pragmatic Trials, Pragmatic Clinical Practical Clinical Trials Clinical Trials, Practical Trials, Practical Clinical

Below are MeSH descriptors whose meaning is more general than "Pragmatic Clinical Trials as Topic".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Epidemiologic Methods [E05.318]
Epidemiologic Study Characteristics [E05.318.760]
Clinical Studies as Topic [E05.318.760.250]
Clinical Trials as Topic [E05.318.760.250.500]
Controlled Clinical Trials as Topic [E05.318.760.250.500.365]
Randomized Controlled Trials as Topic [E05.318.760.250.500.365.500]
Pragmatic Clinical Trials as Topic [E05.318.760.250.500.365.500.500]
Health Care [N]
Health Care Quality, Access, and Evaluation [N05]
Quality of Health Care [N05.715]
Health Care Evaluation Mechanisms [N05.715.360]
Epidemiologic Study Characteristics [N05.715.360.775]
Clinical Studies as Topic [N05.715.360.775.088]
Clinical Trials as Topic [N05.715.360.775.088.500]
Controlled Clinical Trials as Topic [N05.715.360.775.088.500.387]
Randomized Controlled Trials as Topic [N05.715.360.775.088.500.387.500]
Pragmatic Clinical Trials as Topic [N05.715.360.775.088.500.387.500.750]
Environment and Public Health [N06]
Public Health [N06.850]
Epidemiologic Methods [N06.850.520]
Epidemiologic Study Characteristics [N06.850.520.450]
Clinical Studies as Topic [N06.850.520.450.250]
Clinical Trials as Topic [N06.850.520.450.250.250]
Controlled Clinical Trials as Topic [N06.850.520.450.250.250.365]
Randomized Controlled Trials as Topic [N06.850.520.450.250.250.365.500]
Pragmatic Clinical Trials as Topic [N06.850.520.450.250.250.365.500.750]

Below are MeSH descriptors whose meaning is related to "Pragmatic Clinical Trials as Topic".

Below are MeSH descriptors whose meaning is more specific than "Pragmatic Clinical Trials as Topic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pragmatic Clinical Trials as Topic" by people in this website by year, and whether "Pragmatic Clinical Trials as Topic" was a major or minor topic of these publications.

Bar chart showing 27 publications over 11 distinct years, with a maximum of 6 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2014	1	0	1
2015	1	1	2
2018	0	2	2
2019	0	1	1
2020	1	5	6
2021	0	5	5
2022	0	2	2
2023	0	1	1
2024	0	3	3
2025	0	3	3
2026	0	1	1

Below are the most recent publications written about "Pragmatic Clinical Trials as Topic" by people in Profiles.

Hantouli MN, Schmicker RH, Tufte JE, Ali FG, Bennett RD, Cohan JN, Comstock BA, Curran T, Davidson GH, Eisenstein S, Fischkoff KN, Fleming FJ, Gribovskaja-Rupp I, Jafari MD, Kessler LG, Krane MK, Lawrence SO, McCormick JT, Millas SG, Morris AM, Pullar KM, Reinke CE, Saraidaridis JT, Simianu VV, Watkins SP, White NB, Wick EC, Wieghard N, Flum DR, Read TE. Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) trial: a protocol for a pragmatic randomised study of diverticulitis treatment in the USA. BMJ Open. 2026 Jan 08; 16(1):e098309.

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Justice M, Piccorelli A, Avins AL, Cook AJ, Eng CM, Nielsen A, Pressman A, Stone KL, Teets RY, Wellman R, DeBar LL. Baseline sample characteristics for the BackInAction pragmatic trial of acupuncture for chronic low back pain in older adults. Contemp Clin Trials. 2025 Aug; 155:107981.

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Donovan LM, Feemster LC, Collins MP, Gleason EE, Josey K, Duan KI, Plumley R, Coggeshall S, Wai TH, Petrova V, Trenaman L, Atwood M, Ballance P, Baldomero AK, Gillen F, Gunter J, Isaac J, Kara H, Kizer KW, Lambert AA, Liao JM, Lindenauer PK, Llamas W, Martinez N, McDowell J, McFarland MS, McGrath A, Melzer AC, Mog AC, Rommes J, Slatore CG, Strychalski ML, Tanner NT, Yarbrough WC, Au DH. Protocol for a pragmatic trial to enhance quality safety, and patient experience in chronic obstructive pulmonary disease (EQuiP-COPD). Contemp Clin Trials. 2025 Aug; 155:107961.

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Ogdie A, Reddy SM, Gillespie SH, Husni ME, Scher JU, Salomon-Escoto K, Kay J, Luedders BA, Curtis JR, Shields AJS, Chakravarty SD, Gong C, Walsh JA. Guselkumab versus golimumab in patients with active psoriatic arthritis and inadequate response to an initial tumor necrosis factor inhibitor: study protocol for EVOLUTION, a pragmatic, phase 3b, open-label, randomized, controlled effectiveness trial. Trials. 2025 Mar 19; 26(1):96.

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Sellinger JJ, Rosen MI, Lazar CM, Gilstad-Hayden K, Dziura J, Li FY, Mattocks K, Weede A, Sullivan-Tibbs M, Rose L, Garcia Vassallo G, Manhapra A, Turner A, Vogt D, Woodward EN, Hartmann CW, Haskell SG, Mohammad A, Martino S. Screening, brief intervention, and referral to treatment for pain management for veterans separating from military service: study protocol of a hybrid type 2 study testing implementation facilitation versus training-as-usual. Pain Med. 2024 Nov 01; 25(Supplement_1):S99-S106.

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Kawano-Dourado L, Kulkarni T, Ryerson CJ, Rivera-Ortega P, Baldi BG, Chaudhuri N, Funke-Chambour M, Hoffmann-Vold AM, Johannson KA, Khor YH, Montesi SB, Piccari L, Prosch H, Molina-Molina M, Sellares Torres J, Bauer-Ventura I, Rajan S, Jacob J, Richards D, Spencer LG, Wendelberger B, Jensen T, Quintana M, Kreuter M, Gordon AC, Martinez FJ, Kaminski N, Cornelius V, Lewis R, Adams W, Jenkins G. Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung diseases. Thorax. 2024 07 16; 79(8):788-795.

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Singh S, Cocoros NM, Li X, Mazor KM, Antonelli MT, Parlett L, Paullin M, Harkins TP, Zhou Y, Rochon PA, Platt R, Dashevsky I, Massino C, Saphirak C, Crawford SL, Gurwitz JH. Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in the Elderly with Alzheimer's Disease (D-PRESCRIBE-AD): Trial protocol and rationale of an open-label pragmatic, prospective randomized controlled trial. PLoS One. 2024; 19(2):e0297562.

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Cocoros NM, Gurwitz JH, Cziraky MJ, Granger CB, Harkins T, Haynes K, Li X, Parlett L, Seeger JD, Singh S, McMahill-Walraven CN, Platt R. Pragmatic guidance for embedding pragmatic clinical trials in health plans: Large simple trials aren't so simple. Clin Trials. 2023 08; 20(4):416-424.

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Thomas KS, Dosa DM, Fisher A, Gadbois E, Harrison J, Hilgeman M, Largent EA, Lima J, McAuliff K, McCreedy E, Mills W, Ornstein KA, Shield RR, Barron M, Callaghan S, Clark K, Culak C, Faris V, Frankhauser AE, Huerta S, Krause K, Martinez I, Mayer A, Rodriguez J, Theilheimer L, Truelove W, Wilson I, Gutman R. Home-delivered meals for people with dementia: Which model delays nursing home placement? - Protocol for a feasibility pilot. Contemp Clin Trials. 2022 10; 121:106897.

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Ober AJ, Murray-Krezan C, Page K, Friedmann PD, Chan Osilla K, Ryzewicz S, Huerta S, Mazer MW, Leamon I, Messineo G, Watkins KE, Nuckols T, Danovitch I. The Substance Use Treatment and Recovery Team (START) study: protocol for a multi-site randomized controlled trial evaluating an intervention to improve initiation of medication and linkage to post-discharge care for hospitalized patients with opioid use disorder. Addict Sci Clin Pract. 2022 07 28; 17(1):39.

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