Pragmatic Clinical Trials as Topic

"Pragmatic Clinical Trials as Topic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Works about randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and impacts.

Descriptor ID	D064792
MeSH Number(s)	E05.318.760.250.500.365.500.500 N05.715.360.775.088.500.387.500.750 N06.850.520.450.250.250.365.500.750
Concept/Terms	Pragmatic Clinical Trials as Topic Pragmatic Clinical Trials as Topic Real World Clinical Trials Naturalistic Randomized Clinical Trial Pragmatic Trials Trials, Pragmatic Pragmatic Clinical Trials Clinical Trials, Pragmatic Trials, Pragmatic Clinical Practical Clinical Trials Clinical Trials, Practical Trials, Practical Clinical

Below are MeSH descriptors whose meaning is more general than "Pragmatic Clinical Trials as Topic".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Epidemiologic Methods [E05.318]
Epidemiologic Study Characteristics [E05.318.760]
Clinical Studies as Topic [E05.318.760.250]
Clinical Trials as Topic [E05.318.760.250.500]
Controlled Clinical Trials as Topic [E05.318.760.250.500.365]
Randomized Controlled Trials as Topic [E05.318.760.250.500.365.500]
Pragmatic Clinical Trials as Topic [E05.318.760.250.500.365.500.500]
Health Care [N]
Health Care Quality, Access, and Evaluation [N05]
Quality of Health Care [N05.715]
Health Care Evaluation Mechanisms [N05.715.360]
Epidemiologic Study Characteristics [N05.715.360.775]
Clinical Studies as Topic [N05.715.360.775.088]
Clinical Trials as Topic [N05.715.360.775.088.500]
Controlled Clinical Trials as Topic [N05.715.360.775.088.500.387]
Randomized Controlled Trials as Topic [N05.715.360.775.088.500.387.500]
Pragmatic Clinical Trials as Topic [N05.715.360.775.088.500.387.500.750]
Environment and Public Health [N06]
Public Health [N06.850]
Epidemiologic Methods [N06.850.520]
Epidemiologic Study Characteristics [N06.850.520.450]
Clinical Studies as Topic [N06.850.520.450.250]
Clinical Trials as Topic [N06.850.520.450.250.250]
Controlled Clinical Trials as Topic [N06.850.520.450.250.250.365]
Randomized Controlled Trials as Topic [N06.850.520.450.250.250.365.500]
Pragmatic Clinical Trials as Topic [N06.850.520.450.250.250.365.500.750]

Below are MeSH descriptors whose meaning is related to "Pragmatic Clinical Trials as Topic".

Below are MeSH descriptors whose meaning is more specific than "Pragmatic Clinical Trials as Topic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pragmatic Clinical Trials as Topic" by people in this website by year, and whether "Pragmatic Clinical Trials as Topic" was a major or minor topic of these publications.

Bar chart showing 10 publications over 5 distinct years, with a maximum of 4 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2014	1	0	1
2015	1	0	1
2020	1	3	4
2023	0	1	1
2025	0	3	3

Below are the most recent publications written about "Pragmatic Clinical Trials as Topic" by people in Profiles.

Justice M, Piccorelli A, Avins AL, Cook AJ, Eng CM, Nielsen A, Pressman A, Stone KL, Teets RY, Wellman R, DeBar LL. Baseline sample characteristics for the BackInAction pragmatic trial of acupuncture for chronic low back pain in older adults. Contemp Clin Trials. 2025 Aug; 155:107981.

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Donovan LM, Feemster LC, Collins MP, Gleason EE, Josey K, Duan KI, Plumley R, Coggeshall S, Wai TH, Petrova V, Trenaman L, Atwood M, Ballance P, Baldomero AK, Gillen F, Gunter J, Isaac J, Kara H, Kizer KW, Lambert AA, Liao JM, Lindenauer PK, Llamas W, Martinez N, McDowell J, McFarland MS, McGrath A, Melzer AC, Mog AC, Rommes J, Slatore CG, Strychalski ML, Tanner NT, Yarbrough WC, Au DH. Protocol for a pragmatic trial to enhance quality safety, and patient experience in chronic obstructive pulmonary disease (EQuiP-COPD). Contemp Clin Trials. 2025 Aug; 155:107961.

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Ogdie A, Reddy SM, Gillespie SH, Husni ME, Scher JU, Salomon-Escoto K, Kay J, Luedders BA, Curtis JR, Shields AJS, Chakravarty SD, Gong C, Walsh JA. Guselkumab versus golimumab in patients with active psoriatic arthritis and inadequate response to an initial tumor necrosis factor inhibitor: study protocol for EVOLUTION, a pragmatic, phase 3b, open-label, randomized, controlled effectiveness trial. Trials. 2025 Mar 19; 26(1):96.

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Cocoros NM, Gurwitz JH, Cziraky MJ, Granger CB, Harkins T, Haynes K, Li X, Parlett L, Seeger JD, Singh S, McMahill-Walraven CN, Platt R. Pragmatic guidance for embedding pragmatic clinical trials in health plans: Large simple trials aren't so simple. Clin Trials. 2023 08; 20(4):416-424.

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Heapy AA, Driscoll MA, Buta E, LaChappelle KM, Edmond S, Krein SL, Piette JD, Mattocks K, Murphy JL, DeBar L, MacLean RR, Ankawi B, Kawecki T, Martino S, Wagner T, Higgins DM. Co-Operative Pain Education and Self-management (COPES) Expanding Treatment for Real-World Access (ExTRA): Pragmatic Trial Protocol. Pain Med. 2020 12 12; 21(12 Suppl 2):S21-S28.

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Reuben DB, Gill TM, Stevens A, Williamson J, Volpi E, Lichtenstein M, Jennings LA, Tan Z, Evertson L, Bass D, Weitzman L, Carnie M, Wilson N, Araujo K, Charpentier P, Meng C, Greene EJ, Dziura J, Liu J, Unger E, Yang M, Currie K, Lenoir KM, Green AS, Abraham S, Vernon A, Samper-Ternent R, Raji M, Hirst RM, Galloway R, Finney GR, Ladd I, Rahm AK, Borek P, Peduzzi P. D-CARE: The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System-Based Versus Community-Based Dementia Care Versus Usual Dementia Care. J Am Geriatr Soc. 2020 11; 68(11):2492-2499.

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Anstrom KJ, Noth I, Flaherty KR, Edwards RH, Albright J, Baucom A, Brooks M, Clark AB, Clausen ES, Durheim MT, Kim DY, Kirchner J, Oldham JM, Snyder LD, Wilson AM, Wisniewski SR, Yow E, Martinez FJ. Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy - the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial. Respir Res. 2020 Mar 12; 21(1):68.

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Cardet JC, Busse PJ, Carroll JK, Casale TB, Coyne-Beasley T, Dixon-Williams S, Fagan M, Forth VE, Fuhlbrigge AL, Hernandez ML, Kaelber D, Kaplan B, Lorenzi M, Madison S, Maher NE, Majewski K, Manning B, McKee MD, Nazario S, Pace WD, Pencina MJ, Rand CS, Rodriguez-Louis J, She L, Shields J, Teng JE, Wechsler ME, Wisnivesky JP, Yawn BP, Israel E. Adherence to adding inhaled corticosteroids to rescue therapy in a pragmatic trial with adults with asthma: A pilot study. Ann Allergy Asthma Immunol. 2020 05; 124(5):487-493.e1.

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Gill TM, McGloin JM, Latham NK, Charpentier PA, Araujo KL, Skokos EA, Lu C, Shelton A, Bhasin S, Bianco LM, Carnie MB, Covinsky KE, Dykes P, Esserman DA, Ganz DA, Gurwitz JH, Hanson C, Nyquist LV, Reuben DB, Wallace RB, Greene EJ. Screening, Recruitment, and Baseline Characteristics for the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) Study. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1495-1501.

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Larson EB, Tachibana C, Thompson E, Coronado GD, DeBar L, Dember LM, Honda S, Huang SS, Jarvik JG, Nelson C, Septimus E, Simon G, Johnson KE. Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthc (Amst). 2016 Sep; 4(3):138-41.

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