Randomized Controlled Trials as Topic

"Randomized Controlled Trials as Topic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.

Descriptor ID	D016032
MeSH Number(s)	E05.318.760.250.500.365.500 N05.715.360.775.088.500.387.500 N06.850.520.450.250.250.365.500
Concept/Terms	Randomized Controlled Trials as Topic Randomized Controlled Trials as Topic Clinical Trials, Randomized Clinical Trials, Randomized Trials, Randomized Clinical Controlled Clinical Trials, Randomized Controlled Clinical Trials, Randomized

Below are MeSH descriptors whose meaning is more general than "Randomized Controlled Trials as Topic".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Epidemiologic Methods [E05.318]
Epidemiologic Study Characteristics [E05.318.760]
Clinical Studies as Topic [E05.318.760.250]
Clinical Trials as Topic [E05.318.760.250.500]
Controlled Clinical Trials as Topic [E05.318.760.250.500.365]
Randomized Controlled Trials as Topic [E05.318.760.250.500.365.500]
Health Care [N]
Health Care Quality, Access, and Evaluation [N05]
Quality of Health Care [N05.715]
Health Care Evaluation Mechanisms [N05.715.360]
Epidemiologic Study Characteristics [N05.715.360.775]
Clinical Studies as Topic [N05.715.360.775.088]
Clinical Trials as Topic [N05.715.360.775.088.500]
Controlled Clinical Trials as Topic [N05.715.360.775.088.500.387]
Randomized Controlled Trials as Topic [N05.715.360.775.088.500.387.500]
Environment and Public Health [N06]
Public Health [N06.850]
Epidemiologic Methods [N06.850.520]
Epidemiologic Study Characteristics [N06.850.520.450]
Clinical Studies as Topic [N06.850.520.450.250]
Clinical Trials as Topic [N06.850.520.450.250.250]
Controlled Clinical Trials as Topic [N06.850.520.450.250.250.365]
Randomized Controlled Trials as Topic [N06.850.520.450.250.250.365.500]

Below are MeSH descriptors whose meaning is related to "Randomized Controlled Trials as Topic".

Below are MeSH descriptors whose meaning is more specific than "Randomized Controlled Trials as Topic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Randomized Controlled Trials as Topic" by people in this website by year, and whether "Randomized Controlled Trials as Topic" was a major or minor topic of these publications.

Bar chart showing 586 publications over 31 distinct years, with a maximum of 40 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	2	3
1996	1	0	1
1997	0	2	2
1998	0	3	3
1999	1	1	2
2000	1	3	4
2001	1	2	3
2002	1	8	9
2003	1	6	7
2004	2	9	11
2005	0	14	14
2006	5	16	21
2007	9	17	26
2008	2	19	21
2009	3	22	25
2010	3	23	26
2011	7	18	25
2012	8	16	24
2013	5	20	25
2014	5	18	23
2015	4	15	19
2016	8	32	40
2017	3	21	24
2018	1	27	28
2019	6	22	28
2020	4	26	30
2021	1	25	26
2022	1	26	27
2023	4	23	27
2024	9	30	39
2025	4	19	23

Below are the most recent publications written about "Randomized Controlled Trials as Topic" by people in Profiles.

Vaughn VM, Horowitz J, Gandhi T, Neetz RA, Petty L, Hersh A, Lindenauer P, Bernstein SJ, Flanders SA, Harrison JD, Smith JD, White AT, Szymczak JE. Developing an approach to enhance recruitment for a cluster-randomised implementation trial: leveraging deliberative participation and credible messengers. BMJ Open. 2025 Sep 16; 15(9):e094925.

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Reilly ED, Grigorian HL, Heapy AA, Etingen B, Kelly MM, Wolkowicz NR, Girouard CM, Hogan TP, Bernice K, Bickmore T. Assessment of Two Online Interventions for Veterans With Chronic Pain: Protocol for a Randomized Controlled Efficacy Trial. JMIR Res Protoc. 2025 Aug 13; 14:e70601.

View in: PubMed
Bruzios K, Shaffer PM, Blonigen DM, Cucciare MA, Andre M, Byrne T, Smith J, Smelson D. Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial. JMIR Res Protoc. 2025 Jul 18; 14:e70750.

View in: PubMed
Litman HJ, Sheffield KM, Pugach O, Shan M, Lakin P, Cui ZL, Curtis SE, Johnston JA, Harrold LR. Applying Bias Correction Methods to Build Hybrid Controls Using Real-World Patients for a Phase IIb Randomized Controlled Trial of Baricitinib for Rheumatoid Arthritis. Pharm Stat. 2025 Jul-Aug; 24(4):e70020.

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Abdulelah M, Ezenna C, Jenil-Franco A, Jamouss KT, Krishna MM, Joseph M, Chi KY, Dahhan T. Clinical outcomes and safety of sotatercept in pulmonary arterial hypertension: A systematic review and meta-analysis of randomized controlled trials. Vascul Pharmacol. 2025 Sep; 160:107520.

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Seligman HK, Angell SY, Berkowitz SA, Elkind MSV, Hager K, Moise N, Posner H, Muse J, Odoms-Young A, Ridberg R, Troxel AB, Yaroch AL, Volpp KG. A Systematic Review of "Food Is Medicine" Randomized Controlled Trials for Noncommunicable Disease in the United States: A Scientific Statement From the American Heart Association. Circulation. 2025 Jul 29; 152(4):e32-e46.

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Ostermann M, Corteville DC, Doi K, Koyner JL, Lamy A, Li G, Solinsky CM, Winterberg PD, Smith WT, Mehta RL, Murray PT, Shaw AD, Zarbock A, Engelman DT. A phase 3 study of ravulizumab to protect patients with chronic kidney disease from cardiac surgery-associated acute kidney injury and major adverse kidney events (ARTEMIS). Trials. 2025 May 30; 26(1):181.

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Krishna MM, Joseph M, Ezenna C, Pereira V, Rossi R, Akman Z, Rubens M, Mahadevan VS, Nanna MG, Goldsweig AM. TAVR vs. SAVR for severe aortic stenosis in the low and intermediate surgical risk population: An updated meta-analysis, meta-regression, and trial sequential analysis. Cardiovasc Revasc Med. 2025 Oct; 79:78-89.

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McConnell M, Alsager A, Fuchu P, Sriprasad S, Simoncini L, Drainoni ML, Cordova-Ramos EG, Pe?a MM, Madore L, Kalluri NS, Silverstein M, Schofield H, Farah MJ, Fink G, Parker MG. CuddleCard: Protocol for a randomized controlled trial evaluating the effect of providing financial support to low-income mothers of preterm infants on parental caregiving in the neonatal intensive care unit (NICU). BMC Pediatr. 2025 May 15; 25(1):383.

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Lingamsetty SSP, Doma M, Kritya M, Thyagaturu H, Ubaid M, Jitta SR, Prajapati K, Ramadan A, Al-Shammari AS, Martignoni FV, Seto A, Shlofmitz E, Basir MB, Megaly MS, Goldsweig AM. Mechanical outcomes of coronary stenting guided by intravascular ultrasound versus optical coherence tomography: A systematic review and meta-analysis with trial sequential analysis of randomized trials. Int J Cardiol. 2025 Sep 15; 435:133387.

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