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Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors.

Wang Y, Parpia S, Couban R, Wang Q, Armijo-Olivo S, Bassler D, Briel M, Brignardello-Petersen R, Gluud LL, Keitz SA, Letelier LM, Ravaud P, Schulz KF, Siemieniuk RAC, Zeraatkar D, Guyatt GH. Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors. J Clin Epidemiol. 2024 01; 165:111211.

View in: PubMed