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Structure-guided design of a high affinity inhibitor to human CtBP.
Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease.
Inflammasome activation and function in liver disease.
Alcohol and HCV: implications for liver cancer.
Structures and gating mechanism of human TRPM2.
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Structures and gating mechanism of human TRPM2.
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science. 2018 12 21; 362(6421).
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PubMed
subject areas
Adenosine Diphosphate Ribose
Calcium
Cryoelectron Microscopy
Humans
Ion Channel Gating
Protein Domains
Protein Multimerization
Pyrophosphatases
TRPM Cation Channels
authors with profiles
Tianmin Fu PhD