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Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments.
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Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance.
Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant.
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Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant.
Ignatova Z, Gierasch LM. Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant. Proc Natl Acad Sci U S A. 2006 Sep 05; 103(36):13357-61.
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subject areas
Alanine
Amino Acid Sequence
Amino Acid Substitution
Escherichia coli
Exons
Fluoresceins
Fluorescent Dyes
Glutamine
Humans
Huntingtin Protein
In Vitro Techniques
Kinetics
Microscopy, Fluorescence
Models, Biological
Nerve Tissue Proteins
Nuclear Proteins
Organometallic Compounds
Osmolar Concentration
Osmotic Pressure
Proline
Protein Folding
Protein Structure, Secondary
Proteins
Receptors, Retinoic Acid
Recombinant Fusion Proteins
Solubility
Spectrometry, Fluorescence
authors with profiles
Lila M Gierasch Ph.D.