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An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
Caspase-8 mediates inflammation and disease in rodent malaria.
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.
RIG-I: tri-ing to discriminate between self and non-self RNA.
Toll-like Receptors and the Control of Immunity.
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RIG-I: tri-ing to discriminate between self and non-self RNA.
Bowie AG, Fitzgerald KA. RIG-I: tri-ing to discriminate between self and non-self RNA. Trends Immunol. 2007 Apr; 28(4):147-50.
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PubMed
subject areas
Animals
DEAD Box Protein 58
DEAD-box RNA Helicases
Genome, Viral
Humans
Immunologic Surveillance
Receptors, Immunologic
RNA, Viral
Self Tolerance
authors with profiles
Katherine A Fitzgerald PhD