DEAD-box RNA Helicases

"DEAD-box RNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A large family of RNA helicases that share a common protein motif with the single letter amino acid sequence D-E-A-D (Asp-Glu-Ala-Asp). In addition to RNA helicase activity, members of the DEAD-box family participate in other aspects of RNA metabolism and regulation of RNA function.

Descriptor ID	D053487
MeSH Number(s)	D08.811.913.696.445.735.720.249
Concept/Terms	DEAD-box RNA Helicases DEAD-box RNA Helicases DEAD box RNA Helicases Helicases, DEAD-box RNA RNA Helicases, DEAD-box DEAD Box Helicase p68 DEAD Box Helicase p68 p68 RNA Helicase Helicase, p68 RNA RNA Helicase, p68 p68 DEAD Box Protein

Below are MeSH descriptors whose meaning is more general than "DEAD-box RNA Helicases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Nucleotidyltransferases [D08.811.913.696.445]
RNA Nucleotidyltransferases [D08.811.913.696.445.735]
RNA Helicases [D08.811.913.696.445.735.720]
DEAD-box RNA Helicases [D08.811.913.696.445.735.720.249]

Below are MeSH descriptors whose meaning is related to "DEAD-box RNA Helicases".

Below are MeSH descriptors whose meaning is more specific than "DEAD-box RNA Helicases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DEAD-box RNA Helicases" by people in this website by year, and whether "DEAD-box RNA Helicases" was a major or minor topic of these publications.

Bar chart showing 86 publications over 23 distinct years, with a maximum of 10 publications in 2013 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	1	1
2002	0	6	6
2003	0	1	1
2005	0	3	3
2007	1	2	3
2008	2	1	3
2009	5	3	8
2010	4	2	6
2011	2	4	6
2012	3	1	4
2013	5	5	10
2014	3	7	10
2015	1	1	2
2016	2	2	4
2017	1	2	3
2018	1	2	3
2019	1	0	1
2020	1	2	3
2021	2	1	3
2022	0	2	2
2023	0	1	1
2025	0	2	2

Below are the most recent publications written about "DEAD-box RNA Helicases" by people in Profiles.

Smith AJ, Rahat MA, Scaramozza LJ, Eyles SJ, Hardy JA. Inhibition of Zika Virus Protease by Modulating NS2B-NS3 Interactions. Biochemistry. 2026 Jan 06; 65(1):64-76.

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Villacampa N, Sarlus H, Martorell P, Bhalla K, Castro-Gomez S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.

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Heinrich S, Hondele M, Marchand D, Derrer CP, Zedan M, Oswald A, Malinovska L, Uliana F, Khawaja S, Mancini R, Grunwald D, Weis K. Glucose stress causes mRNA retention in nuclear Nab2 condensates. Cell Rep. 2024 01 23; 43(1):113593.

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Dai S, Tang X, Li L, Ishidate T, Ozturk AR, Chen H, Dude AL, Yan YH, Dong MQ, Shen EZ, Mello CC. A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing. Cell Rep. 2022 09 06; 40(10):111265.

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He F, Wu C, Jacobson A. Dcp2 C-terminal cis-binding elements control selective targeting of the decapping enzyme by forming distinct decapping complexes. Elife. 2022 05 23; 11.

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Wu T, Nance J, Chu F, Fazzio TG. Characterization of R-Loop-Interacting Proteins in Embryonic Stem Cells Reveals Roles in rRNA Processing and Gene Expression. Mol Cell Proteomics. 2021; 20:100142.

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Burns W, Bird LM, Heron D, Keren B, Ramachandra D, Thiffault I, Del Viso F, Amudhavalli S, Engleman K, Parenti I, Kaiser FJ, Wierzba J, Riedhammer KM, Liptay S, Zadeh N, Porrmann J, Fischer A, G??wein S, McLaughlin HM, Telegrafi A, Langley KG, Steet R, Louie RJ, Lyons MJ. Syndromic neurodevelopmental disorder associated with de novo variants in DDX23. Am J Med Genet A. 2021 10; 185(10):2863-2872.

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Xia S, Chen Z, Shen C, Fu TM. Higher-order assemblies in immune signaling: supramolecular complexes and phase separation. Protein Cell. 2021 09; 12(9):680-694.

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Brand?o BB, Madsen S, Rabiee A, Oliverio M, Ruiz GP, Ferrucci DL, Branquinho JL, Razolli D, Pinto S, Nielsen TS, Festuccia WT, Martins AS, Guerra BA, Knittel TL, S?gaard D, Larsen S, Helge JW, Brandauer J, Velloso LA, Emanuelli B, Kornfeld JW, Kahn CR, Vienberg SG, Zierath JR, Treebak JT, Mori MA. Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise. Proc Natl Acad Sci U S A. 2020 09 22; 117(38):23932-23941.

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Gon?alves Pereira MH, Figueiredo MM, Queiroz CP, Magalh?es TVB, Mafra A, Diniz LMO, da Costa ?L, Gollob KJ, Antonelli LRDV, Santiago HDC. T-cells producing multiple combinations of IFN?, TNF and IL10 are associated with mild forms of dengue infection. Immunology. 2020 05; 160(1):90-102.

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