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Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
Natural loss-of-function mutation of myeloid differentiation protein 88 disrupts its ability to form Myddosomes.
PtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanism.
Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.
The inflammasomes: mechanisms of activation and function.
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The inflammasomes: mechanisms of activation and function.
Latz E. The inflammasomes: mechanisms of activation and function. Curr Opin Immunol. 2010 Feb; 22(1):28-33.
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PubMed
subject areas
Animals
Caspase 1
Humans
Inflammation
Intercellular Signaling Peptides and Proteins
Interleukin-1beta
Protein Binding
Signal Transduction
authors with profiles
Eicke Latz MD