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Immunogenicity of herpes simplex virus type 1 mutants containing deletions in one or more alpha-genes: ICP4, ICP27, ICP22, and ICP0.
Rapid production of TNF-alpha following TCR engagement of naive CD8 T cells.
Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity.
Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease.
T-cell activation and transplantation tolerance.
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T-cell activation and transplantation tolerance.
Priyadharshini B, Greiner DL, Brehm MA. T-cell activation and transplantation tolerance. Transplant Rev (Orlando). 2012 Jul; 26(3):212-22.
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PubMed
subject areas
Animals
CD8-Positive T-Lymphocytes
Costimulatory and Inhibitory T-Cell Receptors
Graft Rejection
Humans
Isoantigens
Signal Transduction
T-Lymphocytes
Transplantation Tolerance
Tumor Necrosis Factor-alpha
authors with profiles
Michael A Brehm PhD
Dale L Greiner PhD