Necrosis

"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.

Descriptor ID	D009336
MeSH Number(s)	C23.550.717 G04.146.638
Concept/Terms	Necrosis Necrosis Necroses

Below are MeSH descriptors whose meaning is more general than "Necrosis".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Necrosis [C23.550.717]
Biological Sciences [G]
Cell Physiological Phenomena [G04]
Cell Death [G04.146]
Necrosis [G04.146.638]

Below are MeSH descriptors whose meaning is related to "Necrosis".

Below are MeSH descriptors whose meaning is more specific than "Necrosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.

Bar chart showing 115 publications over 28 distinct years, with a maximum of 9 publications in 2014 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
1999	0	2	2
2000	0	2	2
2001	1	0	1
2002	0	2	2
2003	0	6	6
2004	0	5	5
2005	0	2	2
2006	0	2	2
2007	0	3	3
2008	1	3	4
2009	1	4	5
2010	0	7	7
2011	1	7	8
2012	0	6	6
2013	0	4	4
2014	5	4	9
2015	1	3	4
2016	0	3	3
2017	3	4	7
2018	1	8	9
2019	1	4	5
2020	0	6	6
2021	0	1	1
2022	0	4	4
2023	0	2	2
2024	2	1	3
2025	0	1	1

Below are the most recent publications written about "Necrosis" by people in Profiles.

Farzan JJ, Guart JA, Kulkarni N, Roberts S, De la Cruz-Ku G, Czerniach DR, Dinh KH. Managing Necrotizing Soft-Tissue Infection in Breast Cancer: A Case of Emergency Toilet Mastectomy. Am J Case Rep. 2025 May 12; 26:e946669.

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Yarikipati P, Bergmann A. Caspases promote cell proliferation after necrosis. Elife. 2024 Nov 04; 13.

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Karch JL, Grand D, Diaz AG, Belazarian L, Mann JA. Neonatal nasal necrosis: Case series and brief review. Pediatr Dermatol. 2024 Sep-Oct; 41(5):884-887.

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Roderick-Richardson JE, Lim SE, Suzuki S, Ahmad MH, Selway J, Suleiman R, Karna K, Lehman J, O'Donnell J, Castilla LH, Maelfait J, Rehwinkel J, Kelliher MA. ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice. Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4):e2309628121.

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Patil T, Dickson KM, Viera M, Bludevich BM, Akalin A, Uy K, Lou F, Maxfield MW. COVID-19-induced Esophageal Necrosis Requiring Emergent Total Esophagectomy in a Vaccinated Patient. Am Surg. 2023 Nov; 89(11):4999-5001.

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Barry KK, Reusch DB, Shahriari N, Lonowski S, Dedeoglu F, Vleugels RA. Botulinum toxin for refractory Raynaud's phenomenon: A "how to" guide for pediatric patients. Pediatr Dermatol. 2023 May-Jun; 40(3):587-589.

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Yoshida K, Harrold LR, Middaugh N, Guan H, Stryker S, Karis E, Solomon DH. Examining the potential direct cardiovascular benefit of tumor-necrosis factor inhibitor in rheumatoid arthritis: Natural and controlled direct effect analyses. Pharmacoepidemiol Drug Saf. 2023 04; 32(4):407-415.

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McGuire SP, Keller SL, Maatman TK, Lewellen KA, Ceppa EP, House MG, Nakeeb A, Nguyen TK, Quigley SN, Schmidt CM, Zyromski NJ. Obesity Worsens Local and Systemic Complications of Necrotizing Pancreatitis and Prolongs Disease Course. J Gastrointest Surg. 2022 10; 26(10):2128-2135.

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Kerur B, Fiedler K, Stahl M, Hyams J, Stephens M, Lu Y, Pfefferkorn M, Alkhouri R, Strople J, Kelsen J, Siebold L, Goyal A, Rosh JR, LeLeiko N, Van Limbergen J, Guerrerio AL, Maltz RM, Karam L, Crowley E, Griffiths AM, Heyman MB, Deneau M, Benkov K, Noe J, Moulton D, Pappa H, Galanko J, Snapper S, Muise AM, Kappelman MD, Benchimol EI. Utilization of Antitumor Necrosis Factor Biologics in Very Early Onset Inflammatory Bowel Disease: A Multicenter Retrospective Cohort Study From North America. J Pediatr Gastroenterol Nutr. 2022 07 01; 75(1):64-69.

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McGuire SP, Maatman TK, Ceppa EP, House MG, Nakeeb A, Nguyen TK, Schmidt CM, Zyromski NJ. Contemporary Intervention in Necrotizing Pancreatitis: Improved Understanding Changing Practice. J Gastrointest Surg. 2022 07; 26(7):1445-1452.

View in: PubMed

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