 Necrosis
"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. Distinguish it from APOPTOSIS which is a normal, regulated cellular process.
| Descriptor ID |
D009336
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| MeSH Number(s) |
C23.550.717 G04.299.139.638
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Necrosis".
Below are MeSH descriptors whose meaning is more specific than "Necrosis".
This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 0 | 1 | 1 | | 1986 | 0 | 2 | 2 | | 1988 | 1 | 1 | 2 | | 1990 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1995 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 3 | 3 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 3 | 3 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 1 | 6 | 7 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 3 | 3 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 5 | 6 | | 2009 | 0 | 4 | 4 | | 2010 | 0 | 5 | 5 | | 2011 | 1 | 5 | 6 | | 2012 | 0 | 5 | 5 | | 2013 | 0 | 4 | 4 | | 2014 | 4 | 5 | 9 | | 2015 | 0 | 2 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Necrosis" by people in Profiles.
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Giatsidis G. Discussion: Perioperative Treatment with a Prolyl Hydroxylase Inhibitor Reduces Necrosis in a Rat Ischemic Skin Flap Model. Plast Reconstr Surg. 2019 04; 143(4):780e-781e.
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Rhodius P, Haddad A, Matsumine H, Sakthivel D, Ackermann M, Sinha I, Orgill DP, Giatsidis G. Noninvasive Flap Preconditioning by Foam-Mediated External Suction Improves the Survival of Fasciocutaneous Axial-Pattern Flaps in a Type 2 Diabetic Murine Model. Plast Reconstr Surg. 2018 12; 142(6):872e-883e.
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Fantasia J, Brito Iii J, Amin A, Pareek G. Anticipated treatment defect versus prostatic abscess: radiographic findings following transurethral convective radiofrequency-induced water vapor thermal ablation. Can J Urol. 2018 08; 25(4):9424-9426.
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Orzalli MH, Kagan JC. Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection. Trends Cell Biol. 2017 11; 27(11):800-809.
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Chin MS, Chappell AG, Giatsidis G, Perry DJ, Lujan-Hernandez J, Haddad A, Matsumine H, Orgill DP, Lalikos JF. Hyperspectral Imaging Provides Early Prediction of Random Axial Flap Necrosis in a Preclinical Model. Plast Reconstr Surg. 2017 Jun; 139(6):1285e-1290e.
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Galluzzi L, Kepp O, Chan FK, Kroemer G. Necroptosis: Mechanisms and Relevance to Disease. Annu Rev Pathol. 2017 Jan 24; 12:103-130.
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Ito Y, Ofengeim D, Najafov A, Das S, Saberi S, Li Y, Hitomi J, Zhu H, Chen H, Mayo L, Geng J, Amin P, DeWitt JP, Mookhtiar AK, Florez M, Ouchida AT, Fan JB, Pasparakis M, Kelliher MA, Ravits J, Yuan J. RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS. Science. 2016 Aug 5; 353(6299):603-8.
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Thompson CC, Kumar N, Slattery J, Clancy TE, Ryan MB, Ryou M, Swanson RS, Banks PA, Conwell DL. A standardized method for endoscopic necrosectomy improves complication and mortality rates. Pancreatology. 2016 Jan-Feb; 16(1):66-72.
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Cornejo KM, Frazier L, Lee RS, Kozakewich HP, Young RH. Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases. Am J Surg Pathol. 2015 Aug; 39(8):1121-31.
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Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM. SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature. 2015 Apr 16; 520(7547):363-7.
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