Fragile X Mental Retardation Protein

"Fragile X Mental Retardation Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.

Descriptor ID	D051860
MeSH Number(s)	D12.776.157.725.061 D12.776.631.299 D12.776.664.962.124
Concept/Terms	Fragile X Mental Retardation Protein Fragile X Mental Retardation Protein FMRP Protein Fragile X Mental Retardation-1 Protein Fragile X Mental Retardation 1 Protein

Below are MeSH descriptors whose meaning is more general than "Fragile X Mental Retardation Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
RNA-Binding Proteins [D12.776.157.725]
Fragile X Mental Retardation Protein [D12.776.157.725.061]
Nerve Tissue Proteins [D12.776.631]
Fragile X Mental Retardation Protein [D12.776.631.299]
Nucleoproteins [D12.776.664]
RNA-Binding Proteins [D12.776.664.962]
Fragile X Mental Retardation Protein [D12.776.664.962.124]

Below are MeSH descriptors whose meaning is related to "Fragile X Mental Retardation Protein".

Below are MeSH descriptors whose meaning is more specific than "Fragile X Mental Retardation Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fragile X Mental Retardation Protein" by people in this website by year, and whether "Fragile X Mental Retardation Protein" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 2002 and 2003 and 2004 and 2007 and 2008 and 2013 and 2014 and 2017 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2004	0	1	1
2007	0	1	1
2008	1	0	1
2013	1	0	1
2014	1	0	1
2017	0	1	1
2018	1	0	1

Below are the most recent publications written about "Fragile X Mental Retardation Protein" by people in Profiles.

Shah S, Molinaro G, Liu B, Wang R, Huber KM, Richter JD. FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism. Cell Rep. 2020 03 31; 30(13):4459-4472.e6.

View in: PubMed
Liu B, Li Y, Stackpole EE, Novak A, Gao Y, Zhao Y, Zhao X, Richter JD. Regulatory discrimination of mRNAs by FMRP controls mouse adult neural stem cell differentiation. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):E11397-E11405.

View in: PubMed
Gao FB, Richter JD. Microsatellite Expansion Diseases: Repeat Toxicity Found in Translation. Neuron. 2017 Jan 18; 93(2):249-251.

View in: PubMed
Jalnapurkar I, Rafika N, Tassone F, Hagerman R. Immune mediated disorders in women with a fragile X expansion and FXTAS. Am J Med Genet A. 2015 Jan; 167A(1):190-7.

View in: PubMed
Dong S, Walker MF, Carriero NJ, DiCola M, Willsey AJ, Ye AY, Waqar Z, Gonzalez LE, Overton JD, Frahm S, Keaney JF, Teran NA, Dea J, Mandell JD, Hus Bal V, Sullivan CA, DiLullo NM, Khalil RO, Gockley J, Yuksel Z, Sertel SM, Ercan-Sencicek AG, Gupta AR, Mane SM, Sheldon M, Brooks AI, Roeder K, Devlin B, State MW, Wei L, Sanders SJ. De novo insertions and deletions of predominantly paternal origin are associated with autism spectrum disorder. Cell Rep. 2014 Oct 09; 9(1):16-23.

View in: PubMed
Udagawa T, Farny NG, Jakovcevski M, Kaphzan H, Alarcon JM, Anilkumar S, Ivshina M, Hurt JA, Nagaoka K, Nalavadi VC, Lorenz LJ, Bassell GJ, Akbarian S, Chattarji S, Klann E, Richter JD. Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med. 2013 Nov; 19(11):1473-7.

View in: PubMed
Giampetruzzi A, Carson JH, Barbarese E. FMRP and myelin protein expression in oligodendrocytes. Mol Cell Neurosci. 2013 Sep; 56:333-41.

View in: PubMed
Xu XL, Li Y, Wang F, Gao FB. The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila. J Neurosci. 2008 Nov 12; 28(46):11883-9.

View in: PubMed
Gao FB. Posttranscriptional control of neuronal development by microRNA networks. Trends Neurosci. 2008 Jan; 31(1):20-6.

View in: PubMed
Harikrishnan KN, Chow MZ, Baker EK, Pal S, Bassal S, Brasacchio D, Wang L, Craig JM, Jones PL, Sif S, El-Osta A. Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing. Nat Genet. 2005 Mar; 37(3):254-64.

View in: PubMed

People

Explore

Similar Concepts

Top Journals