"Phosphofructokinase-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.
- Phosphofructokinase 2
- ATP-D-Fructose-6-phosphate 2-phosphotransferase
- Fructose-2,6-bisphosphate 2-phosphatase
- Fructose 2,6-bisphosphatase
- 6-Phosphofructo 2-kinase-fructose 2,6-bisphosphatase
- F Kinase-F-bisphosphatase
Below are MeSH descriptors whose meaning is more general than "Phosphofructokinase-2".
Below are MeSH descriptors whose meaning is more specific than "Phosphofructokinase-2".
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Below are the most recent publications written about "Phosphofructokinase-2" by people in Profiles.
Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, Ho IC. A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight. 2016 Oct 20; 1(17):e90045.