von Willebrand Factor

"von Willebrand Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

Descriptor ID	D014841
MeSH Number(s)	D12.776.124.125.920 D23.119.985
Concept/Terms	von Willebrand Factor von Willebrand Factor Factor VIIIR-Ag Factor VIIIR Ag Factor VIIIR-RCo Factor VIIIR RCo Ristocetin-Willebrand Factor Ristocetin Willebrand Factor von Willebrand Protein Factor VIII-Related Antigen Factor VIII Related Antigen Ristocetin Cofactor Plasma Factor VIII Complex Plasma Factor VIII Complex

Below are MeSH descriptors whose meaning is more general than "von Willebrand Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Blood Coagulation Factors [D12.776.124.125]
von Willebrand Factor [D12.776.124.125.920]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
von Willebrand Factor [D23.119.985]

Below are MeSH descriptors whose meaning is more specific than "von Willebrand Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "von Willebrand Factor" by people in this website by year, and whether "von Willebrand Factor" was a major or minor topic of these publications.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 2004 and 2006 and 2008 and 2011 and 2014 and 2019 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	1	1
2006	0	1	1
2008	0	1	1
2011	0	1	1
2014	1	0	1
2019	1	0	1
2022	0	1	1

Below are the most recent publications written about "von Willebrand Factor" by people in Profiles.

Mereuta OM, Abbasi M, Arturo Larco JL, Dai D, Liu Y, Arul S, Kadirvel R, Hanel RA, Yoo AJ, Almekhlafi MA, Layton KF, Delgado Almandoz JE, Kvamme P, Mendes Pereira V, Jahromi BS, Nogueira RG, Gounis MJ, Patel B, Aghaebrahim A, Sauvageau E, Bhuva P, Soomro J, Demchuk AM, Thacker IC, Kayan Y, Copelan A, Nazari P, Cantrell DR, Haussen DC, Al-Bayati AR, Mohammaden M, Pisani L, Rodrigues GM, Puri AS, Entwistle J, Meves A, Savastano L, Cloft HJ, Nimjee SM, McBane RD, Kallmes DF, Brinjikji W. Correlation of von Willebrand factor and platelets with acute ischemic stroke etiology and revascularization outcome: an immunohistochemical study. J Neurointerv Surg. 2023 May; 15(5):488-494.

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Sorvillo N, Mizurini DM, Coxon C, Martinod K, Tilvawala R, Cherpokova D, Salinger AJ, Seward RJ, Staudinger C, Weerapana E, Shapiro NI, Costello CE, Thompson PR, Wagner DD. Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis After Vessel Injury. Circ Res. 2019 08 16; 125(5):507-519.

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Kristofik N, Calabro NE, Tian W, Meng A, MacLauchlan S, Wang Y, Breuer CK, Tellides G, Niklason LE, Kyriakides TR. Impaired von Willebrand factor adhesion and platelet response in thrombospondin-2 knockout mice. Blood. 2016 09 22; 128(12):1642-50.

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Jones CI, Sage T, Moraes LA, Vaiyapuri S, Hussain U, Tucker KL, Barrett NE, Gibbins JM. Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin aIIb?3. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):1968-76.

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Qureshi W, Hassan S, Dabak V, Kuriakose P. Thrombosis in VonWillebrand disease. Thromb Res. 2012 Nov; 130(5):e255-8.

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Bell E, Richardson GD, Jahoda CA, Gledhill K, Phillips HM, Henderson D, Owens WA, Hole N. Dermal stem cells can differentiate down an endothelial lineage. Stem Cells Dev. 2012 Nov 01; 21(16):3019-30.

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Crouthamel MH, Kelly EJ, Ho RJ. Development and characterization of transgenic mouse models for conditional gene knockout in the blood-brain and blood-CSF barriers. Transgenic Res. 2012 Feb; 21(1):113-30.

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Lee H, Meier FA, Ma CK, Ormsby AH, Lee MW. Eosinophilic globules in 3 cases of glomeruloid hemangioma of the head and neck: a characteristic offering more evidence for thanatosomes with or without POEMS. Am J Dermatopathol. 2008 Dec; 30(6):539-44.

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Doldan-Silvero A, Acevedo-Gadea C, Habib C, Freeman J, Johari V. ADAMTS13 activity and inhibitor. Am J Hematol. 2008 Oct; 83(10):811-4.

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Schmugge M, Bang KW, Blanchette VS, Albisetti M, Connolly BL, Freedman J, Rand ML. Platelet activation and von Willebrand factor binding to platelets in newborn infants with central venous lines. Acta Haematol. 2007; 117(3):145-8.

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