G-Quadruplexes

Home
About
Help
History (1)
- G-Quadruplexes
- See All Pages

"G-Quadruplexes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)

Descriptor ID	D054856
MeSH Number(s)	G02.111.570.820.486.550 G05.360.580.550
Concept/Terms	G-Quadruplexes G-Quadruplexes G Quadruplexes Guanine-Quadruplexes Guanine Quadruplexes Guanine-Tetrads Guanine-Tetrads Guanine Tetrads Guanine-Tetrad Guanine-Quartets Guanine Quartets Guanine-Quartet G-Quadruplexes, DNA G-Quadruplexes, DNA G Quadruplexes, DNA Tetraplex DNA DNA, Tetraplex DNA G-Quadruplexes DNA G Quadruplexes DNA, Quadruplex Quadruplex DNA G-Quadruplexes, RNA G-Quadruplexes, RNA G Quadruplexes, RNA RNA G-Quadruplexes RNA, G-Quadruplexes G-Quadruplexes RNA G-Quadruplexes RNAs RNA, G Quadruplexes RNAs, G-Quadruplexes

Below are MeSH descriptors whose meaning is more general than "G-Quadruplexes".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Nucleic Acid Conformation [G02.111.570.820.486]
G-Quadruplexes [G02.111.570.820.486.550]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Nucleic Acid Conformation [G05.360.580]
G-Quadruplexes [G05.360.580.550]

Below are MeSH descriptors whose meaning is related to "G-Quadruplexes".

Below are MeSH descriptors whose meaning is more specific than "G-Quadruplexes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "G-Quadruplexes" by people in this website by year, and whether "G-Quadruplexes" was a major or minor topic of these publications.

Bar chart showing 6 publications over 4 distinct years, with a maximum of 2 publications in 2014 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2014	2	0	2
2020	0	1	1
2021	1	1	2

Below are the most recent publications written about "G-Quadruplexes" by people in Profiles.

Lee WTC, Yin Y, Morten MJ, Tonzi P, Gwo PP, Odermatt DC, Modesti M, Cantor SB, Gari K, Huang TT, Rothenberg E. Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling. Nat Commun. 2021 05 05; 12(1):2525.

View in: PubMed
Lidberg KA, Annalora AJ, Jozic M, Elson DJ, Wang L, Bammler TK, Ramm S, Monteiro MB, Himmelfarb J, Marcus CB, Iversen PL, Kelly EJ. Antisense oligonucleotide development for the selective modulation of CYP3A5 in renal disease. Sci Rep. 2021 02 25; 11(1):4722.

View in: PubMed
Price DA, Kartje ZJ, Hughes JA, Hill TD, Loth TM, Watts JK, Gagnon KT, Moran SD. Infrared Spectroscopy Reveals the Preferred Motif Size and Local Disorder in Parallel Stranded DNA G-Quadruplexes. Chembiochem. 2020 10 01; 21(19):2792-2804.

View in: PubMed
Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, Cudkowicz ME, Boeve BF, Dickson D, Floeter MK, Traynor BJ, Morelli C, Ratti A, Silani V, Rademakers R, Brown RH, Rothstein JD, Boylan KB, Petrucelli L, Disney MD. Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS. Neuron. 2014 Sep 03; 83(5):1043-50.

View in: PubMed
Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, Teruya-Feldstein J, Kelliher MA, Speleman F, Porco JA, Pelletier J, R?tsch G, Wendel HG. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 2014 Sep 04; 513(7516):65-70.

View in: PubMed
Brown BA, Li Y, Brown JC, Hardin CC, Roberts JF, Pelsue SC, Shultz LD. Isolation and characterization of a monoclonal anti-quadruplex DNA antibody from autoimmune "viable motheaten" mice. Biochemistry. 1998 Nov 17; 37(46):16325-37.

View in: PubMed

People

Explore

Similar Concepts

Top Journals