 Actins
"Actins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
| Descriptor ID |
D000199
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| MeSH Number(s) |
D05.750.078.730.250 D12.776.210.500.100 D12.776.220.525.255
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Actins".
Below are MeSH descriptors whose meaning is more specific than "Actins".
This graph shows the total number of publications written about "Actins" by people in this website by year, and whether "Actins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1986 | 1 | 0 | 1 | | 1988 | 1 | 0 | 1 | | 1989 | 0 | 1 | 1 | | 1990 | 0 | 2 | 2 | | 1991 | 1 | 0 | 1 | | 1992 | 2 | 1 | 3 | | 1993 | 1 | 1 | 2 | | 1994 | 1 | 3 | 4 | | 1995 | 0 | 1 | 1 | | 1997 | 2 | 5 | 7 | | 1998 | 2 | 2 | 4 | | 1999 | 4 | 4 | 8 | | 2000 | 6 | 4 | 10 | | 2001 | 3 | 6 | 9 | | 2002 | 6 | 4 | 10 | | 2003 | 4 | 7 | 11 | | 2004 | 7 | 8 | 15 | | 2005 | 7 | 10 | 17 | | 2006 | 2 | 8 | 10 | | 2007 | 3 | 2 | 5 | | 2008 | 3 | 11 | 14 | | 2009 | 5 | 3 | 8 | | 2010 | 5 | 5 | 10 | | 2011 | 5 | 4 | 9 | | 2012 | 3 | 4 | 7 | | 2013 | 0 | 2 | 2 | | 2014 | 3 | 4 | 7 | | 2015 | 3 | 4 | 7 | | 2016 | 1 | 2 | 3 |
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Below are the most recent publications written about "Actins" by people in Profiles.
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Megaw R, Abu-Arafeh H, Jungnickel M, Mellough C, Gurniak C, Witke W, Zhang W, Khanna H, Mill P, Dhillon B, Wright AF, Lako M, Ffrench-Constant C. Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models. Nat Commun. 2017 08 16; 8(1):271.
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He J, Zhou R, Wu Z, Carrasco MA, Kurshan PT, Farley JE, Simon DJ, Wang G, Han B, Hao J, Heller E, Freeman MR, Shen K, Maniatis T, Tessier-Lavigne M, Zhuang X. Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):6029-34.
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Fallini C, Donlin-Asp PG, Rouanet JP, Bassell GJ, Rossoll W. Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons. J Neurosci. 2016 Mar 30; 36(13):3811-20.
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Hjortnaes J, Goettsch C, Hutcheson JD, Camci-Unal G, Lax L, Scherer K, Body S, Schoen FJ, Kluin J, Khademhosseini A, Aikawa E. Simulation of early calcific aortic valve disease in a 3D platform: A role for myofibroblast differentiation. J Mol Cell Cardiol. 2016 05; 94:13-20.
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Saslowsky DE, Thiagarajah JR, McCormick BA, Lee JC, Lencer WI. Microbial sphingomyelinase induces RhoA-mediated reorganization of the apical brush border membrane and is protective against invasion. Mol Biol Cell. 2016 Apr 01; 27(7):1120-30.
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Mun JY, Kensler RW, Harris SP, Craig R. The cMyBP-C HCM variant L348P enhances thin filament activation through an increased shift in tropomyosin position. J Mol Cell Cardiol. 2016 Feb; 91:141-7.
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Kural MH, Billiar KL. Myofibroblast persistence with real-time changes in boundary stiffness. Acta Biomater. 2016 Mar 01; 32:223-30.
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Romarowski A, Battistone MA, La Spina FA, Puga Molina Ldel C, Luque GM, Vitale AM, Cuasnicu PS, Visconti PE, Krapf D, Buffone MG. PKA-dependent phosphorylation of LIMK1 and Cofilin is essential for mouse sperm acrosomal exocytosis. Dev Biol. 2015 Sep 15; 405(2):237-49.
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Burkart GM, Baskin TI, Bezanilla M. A family of ROP proteins that suppresses actin dynamics, and is essential for polarized growth and cell adhesion. J Cell Sci. 2015 Jul 15; 128(14):2553-64.
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RodrÃguez D, Cornejo KM, Sadow PM, Santiago-Lastra Y, Feldman AS. Myopericytoma tumor of the glans penis. Can J Urol. 2015 Jun; 22(3):7830-3.
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