"Gelsolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.
| Descriptor ID |
D018260
|
| MeSH Number(s) |
D05.750.078.730.350 D12.644.360.372.437 D12.776.157.125.412.437 D12.776.220.525.350 D12.776.476.387.437
|
| Concept/Terms |
Gelsolin- Gelsolin
- Gelsolin Protein
- Serum Actin Inhibitory Protein
|
Below are MeSH descriptors whose meaning is more general than "Gelsolin".
Below are MeSH descriptors whose meaning is more specific than "Gelsolin".
This graph shows the total number of publications written about "Gelsolin" by people in this website by year, and whether "Gelsolin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Gelsolin" by people in Profiles.
-
Megaw R, Abu-Arafeh H, Jungnickel M, Mellough C, Gurniak C, Witke W, Zhang W, Khanna H, Mill P, Dhillon B, Wright AF, Lako M, Ffrench-Constant C. Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models. Nat Commun. 2017 08 16; 8(1):271.
-
Clement CC, Becerra A, Yin L, Zolla V, Huang L, Merlin S, Follenzi A, Shaffer SA, Stern LJ, Santambrogio L. The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity. J Biol Chem. 2016 Mar 11; 291(11):5576-5595.
-
Karakis I, Jones HR, Gajjar AA, Baharozian DB, Srinivasan J. Teaching NeuroImages: gelsolin-related amyloidosis: a rare cause of progressive facial diparesis. Neurology. 2013 Feb 26; 80(9):e94.
-
Turvey MR, Fogarty KE, Thorn P. Inositol (1,4,5)-trisphosphate receptor links to filamentous actin are important for generating local Ca2+ signals in pancreatic acinar cells. J Cell Sci. 2005 Mar 01; 118(Pt 5):971-80.
-
Gong H, Hatch V, Ali L, Lehman W, Craig R, Tobacman LS. Mini-thin filaments regulated by troponin-tropomyosin. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):656-61.
-
Hidalgo C, Padr?n R, Horowitz R, Zhao FQ, Craig R. Purification of native myosin filaments from muscle. Biophys J. 2001 Nov; 81(5):2817-26.