 Streptozocin
"Streptozocin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
| Descriptor ID |
D013311
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| MeSH Number(s) |
D02.654.692.768 D02.948.594.768 D09.408.051.900
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| Concept/Terms |
Streptozocin- Streptozocin
- Streptozotocin
- Streptozotocine
- 2-Deoxy-2-((methylnitrosoamino)carbonyl)amino-D-glucose
Zanosar- Zanosar
- Teva Brand of Streptozocin
- Streptozocin Teva Brand
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Below are MeSH descriptors whose meaning is more general than "Streptozocin".
Below are MeSH descriptors whose meaning is more specific than "Streptozocin".
This graph shows the total number of publications written about "Streptozocin" by people in this website by year, and whether "Streptozocin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1983 | 1 | 0 | 1 | | 1986 | 1 | 0 | 1 | | 1988 | 2 | 0 | 2 | | 1989 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 2001 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2008 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Streptozocin" by people in Profiles.
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Mellado-Gil J, Rosa TC, Demirci C, Gonzalez-Pertusa JA, Velazquez-Garcia S, Ernst S, Valle S, Vasavada RC, Stewart AF, Alonso LC, Garcia-Ocaña A. Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes. Diabetes. 2011 Feb; 60(2):525-36.
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Amaral S, Mota PC, Lacerda B, Alves M, Pereira Mde L, Oliveira PJ, Ramalho-Santos J. Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats. Mitochondrion. 2009 Feb; 9(1):41-50.
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Hsu PY, Kotin RM, Yang YW. Glucose- and metabolically regulated hepatic insulin gene therapy for diabetes. Pharm Res. 2008 Jun; 25(6):1460-8.
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Tal MG, Hirshberg B, Neeman Z, Bunnell D, Soleimanpour S, Bacher J, Patterson N, Chang R, Harlan DM. Induction of diabetes in nonhuman primates by means of temporary arterial embolization and selective arterial injection of streptozotocin. Radiology. 2004 Jan; 230(1):163-8.
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Pechhold K, Patterson NB, Blum C, Fleischacker CL, Boehm BO, Harlan DM. Low dose streptozotocin-induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent. J Immunol. 2001 Feb 15; 166(4):2531-9.
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Stark J, Baffour R, Garb JL, Kaufman J, Berman J, Rhee S, Norris MA, Friedmann P. Basic fibroblast growth factor stimulates angiogenesis in the hindlimb of hyperglycemic rats. J Surg Res. 1998 Sep; 79(1):8-12.
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Chipkin SR, van Bueren A, Bercel E, Garrison CR, McCall AL. Effects of dexamethasone in vivo and in vitro on hexose transport in brain microvasculature. Neurochem Res. 1998 May; 23(5):645-52.
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Harlan DM, Barnett MA, Abe R, Pechhold K, Patterson NB, Gray GS, June CH. Very-low-dose streptozotocin induces diabetes in insulin promoter-mB7-1 transgenic mice. Diabetes. 1995 Jul; 44(7):816-23.
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Gerling IC, Friedman H, Greiner DL, Shultz LD, Leiter EH. Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes. Diabetes. 1994 Mar; 43(3):433-40.
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Fram RJ, Mack SL, George M, Marinus MG. DNA repair mechanisms affecting cytotoxicity by streptozotocin in E. coli. Mutat Res. 1989 Sep; 218(2):125-33.
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