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Polyadenylation

"Polyadenylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAUAAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here.


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This graph shows the total number of publications written about "Polyadenylation" by people in this website by year, and whether "Polyadenylation" was a major or minor topic of these publications.
Bar chart showing 32 publications over 16 distinct years, with a maximum of 3 publications in 2005 and 2006 and 2012 and 2013 and 2018
To see the data from this visualization as text, click here.