Factor Xa

"Factor Xa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.

Descriptor ID	D015951
MeSH Number(s)	D08.811.277.656.300.760.315 D08.811.277.656.959.350.315 D12.776.124.125.400.315 D23.119.400.315
Concept/Terms	Factor Xa Factor Xa Factor Ten A Activated Factor X Factor X, Activated Coagulation Factor Xa Factor Xa, Coagulation Blood Coagulation Factor X, Activated Thrombokinase Factor 10A Autoprothrombin C

Below are MeSH descriptors whose meaning is more general than "Factor Xa".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Endopeptidases [D08.811.277.656.300]
Serine Endopeptidases [D08.811.277.656.300.760]
Factor Xa [D08.811.277.656.300.760.315]
Serine Proteases [D08.811.277.656.959]
Serine Endopeptidases [D08.811.277.656.959.350]
Factor Xa [D08.811.277.656.959.350.315]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Blood Coagulation Factors [D12.776.124.125]
Factor X [D12.776.124.125.400]
Factor Xa [D12.776.124.125.400.315]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
Factor X [D23.119.400]
Factor Xa [D23.119.400.315]

Below are MeSH descriptors whose meaning is more specific than "Factor Xa".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Factor Xa" by people in this website by year, and whether "Factor Xa" was a major or minor topic of these publications.

Bar chart showing 7 publications over 6 distinct years, with a maximum of 2 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2008	0	1	1
2012	0	1	1
2018	1	1	2
2020	1	0	1
2023	0	1	1

Below are the most recent publications written about "Factor Xa" by people in Profiles.

Huang J, Mazer CD, Boisen ML, Tibi P, Baker RA, Chu D, Moffatt-Bruce S, Shore-Lesserson L. Safety of Andexanet Alfa Use in Cardiac Surgery. J Cardiothorac Vasc Anesth. 2023 07; 37(7):1332-1334.

View in: PubMed
Lawlor M, Gupta A, Ranard LS, Madhavan MV, Li J, Eisenberger A, Parikh SA, Sethi SS, Masoumi A. Discordance in activated partial thromboplastin time and anti-factor Xa levels in COVID-19 patients on heparin therapy. Thromb Res. 2021 02; 198:79-82.

View in: PubMed
Minsky BB, Abzalimov RR, Niu C, Zhao Y, Kirsch Z, Dubin PL, Savinov SN, Kaltashov IA. Mass Spectrometry Reveals a Multifaceted Role of Glycosaminoglycan Chains in Factor Xa Inactivation by Antithrombin. Biochemistry. 2018 08 14; 57(32):4880-4890.

View in: PubMed
Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Bl?her M, Czech MP, Tabas I. Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance. Nature. 2018 03 29; 555(7698):673-677.

View in: PubMed
Liveris A, Bello RA, Friedmann P, Duffy MA, Manwani D, Killinger JS, Rodriquez D, Weinstein S. Anti-factor Xa assay is a superior correlate of heparin dose than activated partial thromboplastin time or activated clotting time in pediatric extracorporeal membrane oxygenation*. Pediatr Crit Care Med. 2014 Feb; 15(2):e72-9.

View in: PubMed
Gopalakrishnan L, Kumar V, Kohli P, Singh P, Rastogi U, Gibson CM. Pharmacokinetic evaluation of rivaroxaban for the treatment of acute coronary syndromes. Expert Opin Drug Metab Toxicol. 2012 Jul; 8(7):889-900.

View in: PubMed
Thomas BE, Woznica I, Mierke DF, Wittelsberger A, Rosenblatt M. Conformational changes in the parathyroid hormone receptor associated with activation by agonist. Mol Endocrinol. 2008 May; 22(5):1154-62.

View in: PubMed
Leung R, Gwozdz AM, Wang H, Bang KW, Packham MA, Freedman J, Rand ML. Persistence of procoagulant surface expression on activated human platelets: involvement of apoptosis and aminophospholipid translocase activity. J Thromb Haemost. 2007 Mar; 5(3):560-70.

View in: PubMed
Barnard MR, Linden MD, Frelinger AL, Li Y, Fox ML, Furman MI, Michelson AD. Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity. J Thromb Haemost. 2005 Nov; 3(11):2563-70.

View in: PubMed
Becker RC, Alexander J, Li YF, Bovill E, Spencer FA, Robertson TL, Kunitada S, Dyke CK, Harrington RA. Combined coagulation phase-directed factor Xa inhibition with heparin compounds and DX-9065a - a direct and selective antagonist. Thromb Haemost. 2004 Dec; 92(6):1229-31.

View in: PubMed

People

Explore

Similar Concepts

Top Journals