"Chymases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of neutral serine proteases with CHYMOTRYPSIN-like activity. Chymases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
| Descriptor ID |
D053818
|
| MeSH Number(s) |
D08.811.277.656.300.760.103 D08.811.277.656.959.350.103
|
| Concept/Terms |
Chymases- Chymases
- Chymase
- Chymotrypsin-Like Proteases
- Chymotrypsin Like Proteases
- Chymotrypsin-Like Protease
- Chymotrypsin Like Protease
- Chymase-1
- Chymase 1
|
Below are MeSH descriptors whose meaning is more general than "Chymases".
Below are MeSH descriptors whose meaning is more specific than "Chymases".
This graph shows the total number of publications written about "Chymases" by people in this website by year, and whether "Chymases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chymases" by people in Profiles.
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Sundaram A, Chen C, Khalifeh-Soltani A, Atakilit A, Ren X, Qiu W, Jo H, DeGrado W, Huang X, Sheppard D. Targeting integrin a5?1 ameliorates severe airway hyperresponsiveness in experimental asthma. J Clin Invest. 2017 01 03; 127(1):365-374.
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Ogbu CO, Qabar MN, Boatman PD, Urban J, Meara JP, Ferguson MD, Tulinsky J, Lum C, Babu S, Blaskovich MA, Nakanishi H, Ruan F, Cao B, Minarik R, Little T, Nelson S, Nguyen M, Gall A, Kahn M. Highly efficient and versatile synthesis of libraries of constrained beta-strand mimetics. Bioorg Med Chem Lett. 1998 Sep 08; 8(17):2321-6.
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Castagliuolo I, Leeman SE, Bartolak-Suki E, Nikulasson S, Qiu B, Carraway RE, Pothoulakis C. A neurotensin antagonist, SR 48692, inhibits colonic responses to immobilization stress in rats. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12611-5.
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Fischer AR, Rosenberg MA, Lilly CM, Callery JC, Rubin P, Cohn J, White MV, Igarashi Y, Kaliner MA, Drazen JM, et al. Direct evidence for a role of the mast cell in the nasal response to aspirin in aspirin-sensitive asthma. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 1):1046-56.
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Cochrane DE, Carraway RE, Feldberg RS, Boucher W, Gelfand JM. Stimulated rat mast cells generate histamine-releasing peptide from albumin. Peptides. 1993 Mar-Apr; 14(2):117-23.