Sialyltransferases

"Sialyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of enzymes with the general formula CMP-N-acetylneuraminate:acceptor N-acetylneuraminyl transferase. They catalyze the transfer of N-acetylneuraminic acid from CMP-N-acetylneuraminic acid to an acceptor, which is usually the terminal sugar residue of an oligosaccharide, a glycoprotein, or a glycolipid. EC 2.4.99.-.

Descriptor ID	D012799
MeSH Number(s)	D08.811.913.400.800
Concept/Terms	Sialyltransferases Sialyltransferases Glycoprotein Sialyltransferase Glycoprotein Sialyltransferase Sialyltransferase, Glycoprotein Glycoprotein Sialyltransferases Sialyltransferases, Glycoprotein Ectosialyltransferase Ectosialyltransferase

Below are MeSH descriptors whose meaning is more general than "Sialyltransferases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Glycosyltransferases [D08.811.913.400]
Sialyltransferases [D08.811.913.400.800]

Below are MeSH descriptors whose meaning is related to "Sialyltransferases".

Below are MeSH descriptors whose meaning is more specific than "Sialyltransferases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Sialyltransferases" by people in this website by year, and whether "Sialyltransferases" was a major or minor topic of these publications.

Bar chart showing 13 publications over 7 distinct years, with a maximum of 3 publications in 2020 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2015	2	0	2
2017	1	0	1
2019	1	0	1
2020	1	2	3
2021	2	0	2
2023	0	3	3

Below are the most recent publications written about "Sialyltransferases" by people in Profiles.

Dookwah M, Wagner SK, Ishihara M, Yu SH, Ulrichs H, Kulik MJ, Zeltner N, Dalton S, Strauss KA, Aoki K, Steet R, Tiemeyer M. Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 synthase deficiency variants. Hum Mol Genet. 2023 12 01; 32(24):3323-3341.

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Bhalerao N, Chakraborty A, Marciel MP, Hwang J, Britain CM, Silva AD, Eltoum IE, Jones RB, Alexander KL, Smythies LE, Smith PD, Crossman DK, Crowley MR, Shin B, Harrington LE, Yan Z, Bethea MM, Hunter CS, Klug CA, Buchsbaum DJ, Bellis SL. ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression. JCI Insight. 2023 10 09; 8(19).

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Yang H, Brown RH, Wang D, Strauss KA, Gao G. Rescue of GM3 synthase deficiency by spatially controlled, rAAV-mediated ST3GAL5 delivery. JCI Insight. 2023 05 08; 8(9).

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Dorsett KA, Marciel MP, Hwang J, Ankenbauer KE, Bhalerao N, Bellis SL. Regulation of ST6GAL1 sialyltransferase expression in cancer cells. Glycobiology. 2021 06 03; 31(5):530-539.

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Yang H, Brown RH, Wang D, Strauss KA, Gao G. AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies. Trends Mol Med. 2021 06; 27(6):520-523.

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Britain CM, Bhalerao N, Silva AD, Chakraborty A, Buchsbaum DJ, Crowley MR, Crossman DK, Edwards YJK, Bellis SL. Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells. J Biol Chem. 2021 Jan-Jun; 296:100034.

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Gulati S, Schoenhofen IC, Lindhout-Djukic T, Lewis LA, Moustafa IY, Saha S, Zheng B, Nowak N, Rice PA, Varki A, Ram S. Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins. J Infect Dis. 2020 10 13; 222(10):1641-1650.

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Gulati S, Schoenhofen IC, Lindhout-Djukic T, Schur MJ, Landig CS, Saha S, Deng L, Lewis LA, Zheng B, Varki A, Ram S. Therapeutic CMP-Nonulosonates against Multidrug-Resistant Neisseria gonorrhoeae. J Immunol. 2020 06 15; 204(12):3283-3295.

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Bowser LE, Young M, Wenger OK, Ammous Z, Brigatti KW, Carson VJ, Moser T, Deline J, Aoki K, Morlet T, Scott EM, Puffenberger EG, Robinson DL, Hendrickson C, Salvin J, Gottlieb S, Heaps AD, Tiemeyer M, Strauss KA. Recessive GM3 synthase deficiency: Natural history, biochemistry, and therapeutic frontier. Mol Genet Metab. 2019 04; 126(4):475-488.

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Inokuchi JI, Go S, Yoshikawa M, Strauss K. Gangliosides and hearing. Biochim Biophys Acta Gen Subj. 2017 Oct; 1861(10):2485-2493.

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