Cyclooxygenase 2

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"Cyclooxygenase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.

Descriptor ID	D051546
MeSH Number(s)	D08.811.600.720.750
Concept/Terms	Cyclooxygenase 2 Cyclooxygenase 2 Cyclo-Oxygenase II Cyclo Oxygenase II PTGS2 PGHS-2 Prostaglandin H Synthase-2 Prostaglandin H Synthase 2 COX-2 Prostaglandin Synthase COX 2 Prostaglandin Synthase Prostaglandin Synthase, COX-2 Synthase, COX-2 Prostaglandin Cyclooxygenase-2

Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase 2".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Multienzyme Complexes [D08.811.600]
Prostaglandin-Endoperoxide Synthases [D08.811.600.720]
Cyclooxygenase 2 [D08.811.600.720.750]

Below are MeSH descriptors whose meaning is related to "Cyclooxygenase 2".

Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase 2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclooxygenase 2" by people in this website by year, and whether "Cyclooxygenase 2" was a major or minor topic of these publications.

Bar chart showing 65 publications over 23 distinct years, with a maximum of 10 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2000	0	2	2
2001	0	1	1
2002	0	9	9
2003	0	2	2
2004	0	10	10
2005	1	4	5
2006	1	4	5
2007	0	1	1
2008	0	2	2
2009	1	2	3
2010	3	5	8
2011	1	0	1
2013	0	1	1
2015	0	2	2
2016	0	2	2
2017	0	1	1
2018	1	3	4
2019	1	0	1
2020	0	1	1
2021	0	1	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Cyclooxygenase 2" by people in Profiles.

Gong Z, Li Q, Shi J, Li P, Hua L, Shultz LD, Ren G. Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis. Sci Immunol. 2023 02 24; 8(80):eadd5204.

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Gong Z, Li Q, Shi J, Wei J, Li P, Chang CH, Shultz LD, Ren G. Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment. Immunity. 2022 08 09; 55(8):1483-1500.e9.

View in: PubMed
Guo S, Wu X, Zheng J, Smith SA, Dong P, Xiao H. Identification of 4'-Demethyltangeretin as a Major Urinary Metabolite of Tangeretin in Mice and Its Anti-inflammatory Activities. J Agric Food Chem. 2021 Apr 21; 69(15):4381-4391.

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Chen H, Wang K, Xiao H, Hu Z, Zhao L. Structural Characterization and Pro-inflammatory Activity of a Thaumatin-Like Protein from Pulp Tissues of Litchi chinensis. J Agric Food Chem. 2020 Jun 10; 68(23):6439-6447.

View in: PubMed
Walker ME, Matthan NR, Goldbaum A, Meng H, Lamon-Fava S, Lakshman S, Jang S, Molokin A, Solano-Aguilar G, Urban JF, Lichtenstein AH. Dietary patterns influence epicardial adipose tissue fatty acid composition and inflammatory gene expression in the Ossabaw pig. J Nutr Biochem. 2019 08; 70:138-146.

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Park EJ, Sang-Ngern M, Chang LC, Pezzuto JM. Physalactone and 4?-Hydroxywithanolide E Isolated from Physalis peruviana Inhibit LPS-Induced Expression of COX-2 and iNOS Accompanied by Abatement of Akt and STAT1. J Nat Prod. 2019 03 22; 82(3):492-499.

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Wu X, Song M, Cai X, Neto C, Tata A, Han Y, Wang Q, Tang Z, Xiao H. Chemopreventive Effects of Whole Cranberry (Vaccinium macrocarpon) on Colitis-Associated Colon Tumorigenesis. Mol Nutr Food Res. 2018 12; 62(24):e1800942.

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Elling R, Robinson EK, Shapleigh B, Liapis SC, Covarrubias S, Katzman S, Groff AF, Jiang Z, Agarwal S, Motwani M, Chan J, Sharma S, Hennessy EJ, FitzGerald GA, McManus MT, Rinn JL, Fitzgerald KA, Carpenter S. Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2. Cell Rep. 2018 11 06; 25(6):1511-1524.e6.

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Rakariyatham K, Wu X, Tang Z, Han Y, Wang Q, Xiao H. Synergism between luteolin and sulforaphane in anti-inflammation. Food Funct. 2018 Oct 17; 9(10):5115-5123.

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Guo S, Wu X, Zheng J, Charoensinphon N, Dong P, Qiu P, Song M, Tang Z, Xiao H. Anti-inflammatory effect of xanthomicrol, a major colonic metabolite of 5-demethyltangeretin. Food Funct. 2018 Jun 20; 9(6):3104-3113.

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