tau Proteins

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"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).

Descriptor ID	D016875
MeSH Number(s)	D12.776.220.600.450.510 D12.776.631.560.510
Concept/Terms	tau Proteins tau Proteins Proteins, tau tau Protein Protein, tau

Below are MeSH descriptors whose meaning is more general than "tau Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Cytoskeletal Proteins [D12.776.220]
Microtubule Proteins [D12.776.220.600]
Microtubule-Associated Proteins [D12.776.220.600.450]
tau Proteins [D12.776.220.600.450.510]
Nerve Tissue Proteins [D12.776.631]
Microtubule-Associated Proteins [D12.776.631.560]
tau Proteins [D12.776.631.560.510]

Below are MeSH descriptors whose meaning is related to "tau Proteins".

Below are MeSH descriptors whose meaning is more specific than "tau Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.

Bar chart showing 89 publications over 25 distinct years, with a maximum of 10 publications in 2019 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2001	0	1	1
2002	1	1	2
2003	1	0	1
2004	3	1	4
2005	2	3	5
2006	3	2	5
2007	4	0	4
2008	2	0	2
2009	2	1	3
2010	0	1	1
2011	1	3	4
2012	1	0	1
2013	1	1	2
2014	1	1	2
2015	0	1	1
2016	2	0	2
2017	1	1	2
2018	1	2	3
2019	5	5	10
2020	2	5	7
2021	1	1	2
2022	0	10	10
2023	0	5	5
2024	6	3	9

Below are the most recent publications written about "tau Proteins" by people in Profiles.

Bell TR, Franz CE, Thomas KR, Williams ME, Eyler LT, Lerman I, Fennema-Notestine C, Puckett OK, Dorros SM, Panizzon MS, Pearce RC, Hagler DJ, Lyons MJ, Elman JA, Kremen WS. Elevated C-Reactive Protein in Older Men With Chronic Pain: Association With Plasma Amyloid Levels and Hippocampal Volume. J Gerontol A Biol Sci Med Sci. 2024 Nov 01; 79(11).

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Lam AD, Thibault EG, Mayblyum DV, Hsieh S, Pellerin KR, Sternberg EJ, Viswanathan A, Buss S, Sarkis RA, Jacobs HIL, Johnson KA, Sperling RA. Association of Seizure Foci and Location of Tau and Amyloid Deposition and Brain Atrophy in Patients With Alzheimer Disease and Seizures. Neurology. 2024 Nov 12; 103(9):e209920.

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Liu S, Park T, Kr?ger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers. Alzheimers Dement. 2024 Nov; 20(11):7698-7714.

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Scheiblich H, Eikens F, Wischhof L, Opitz S, J?ngling K, Cser?p C, Schmidt SV, Lambertz J, Bellande T, P?sfai B, Geck C, Spitzer J, Odainic A, Castro-Gomez S, Schwartz S, Boussaad I, Kr?ger R, Glaab E, Di Monte DA, Bano D, D?nes ?, Latz E, Melki R, Pape HC, Heneka MT. Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes. Neuron. 2024 Sep 25; 112(18):3106-3125.e8.

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Chatterjee M, ?zdemir S, Fritz C, M?bius W, Kleineidam L, Mandelkow E, Biernat J, Dogdu C, Peters O, Cosma NC, Wang X, Schneider LS, Priller J, Spruth E, K?hn AA, Krause P, Klockgether T, Vogt IR, Kimmich O, Spottke A, Hoffmann DC, Fliessbach K, Miklitz C, McCormick C, Weydt P, Falkenburger B, Brandt M, Guenther R, Dinter E, Wiltfang J, Hansen N, B?hr M, Zerr I, Fl?el A, Nestor PJ, D?zel E, Glanz W, Incesoy E, B?rger K, Janowitz D, Perneczky R, Rauchmann BS, Hopfner F, Wagemann O, Levin J, Teipel S, Kilimann I, Goerss D, Prudlo J, Gasser T, Brockmann K, Mengel D, Zimmermann M, Synofzik M, Wilke C, Selma-Gonz?lez J, Turon-Sans J, Santos-Santos MA, Alcolea D, Rubio-Guerra S, Fortea J, Carbayo ?, Lle? A, Rojas-Garc?a R, Ill?n-Gala I, Wagner M, Frommann I, Roeske S, Bertram L, Heneka MT, Brosseron F, Ramirez A, Schmid M, Beschorner R, Halle A, Herms J, Neumann M, Barth?lemy NR, Bateman RJ, Rizzu P, Heutink P, Dols-Icardo O, H?glinger G, Hermann A, Schneider A. Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS. Nat Med. 2024 Jun; 30(6):1771-1783.

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Talavera And?jar B, Mary A, Venegas C, Cheng T, Zaslavsky L, Bolton EE, Heneka MT, Schymanski EL. Can Small Molecules Provide Clues on Disease Progression in Cerebrospinal Fluid from Mild Cognitive Impairment and Alzheimer's Disease Patients? Environ Sci Technol. 2024 Mar 05; 58(9):4181-4192.

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Cousins KAQ, Irwin DJ, Tropea TF, Rhodes E, Phillips J, Chen-Plotkin AS, Brumm MC, Coffey CS, Kang JH, Simuni T, Foroud TM, Toga AW, Tanner CM, Kieburtz KD, Mollenhauer B, Galasko D, Hutten S, Weintraub D, Siderowf AD, Marek K, Poston KL, Shaw LM. Evaluation of ATNPD Framework and Biofluid Markers to Predict Cognitive Decline in Early Parkinson Disease. Neurology. 2024 Feb; 102(4):e208033.

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Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Bartels C, Rostamzadeh A, Glanz W, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Mengel D, Synofzik M, Munk MH, Spottke A, Roy N, Roeske S, Kuhn E, Ramirez A, Dobisch L, Schmid M, Berger M, Wolfsgruber S, Yakupov R, Hetzer S, Dechent P, Ewers M, Scheffler K, Schott BH, Schreiber S, Orellana A, de Rojas I, Marqui? M, Boada M, Sotolongo O, Gonz?lez PG, Puerta R, D?zel E, Jessen F, Wagner M, Ruiz A, Heneka MT, Maass A. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Mol Psychiatry. 2024 Apr; 29(4):992-1004.

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Bell TR, Franz CE, Eyler LT, Fennema-Notestine C, Puckett OK, Dorros SM, Panizzon MS, Pearce RC, Hagler DJ, Lyons MJ, Beck A, Elman JA, Kremen WS. Probable chronic pain, brain structure, and Alzheimer's plasma biomarkers in older men. J Pain. 2024 Jun; 25(6):104463.

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Stark M, Wolfsgruber S, Kleineidam L, Frommann I, Altenstein S, Bartels C, Brosseron F, Buerger K, Burow L, Butryn M, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, Gref D, Hansen N, Heneka MT, Hinderer P, Incesoy EI, Janowitz D, Kilimann I, Kimmich O, Laske C, Munk MH, Perneczky R, Peters O, Preis L, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Sanzenbacher C, Schneider A, Schott BH, Spottke A, Spruth EJ, Teipel S, Vogt IR, Wiltfang J, Duzel E, Jessen F, Wagner M. Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline. Neurology. 2023 Nov 21; 101(21):e2185-e2196.

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