Mitogen-Activated Protein Kinase 6
"Mitogen-Activated Protein Kinase 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX.
Descriptor ID |
D048053
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MeSH Number(s) |
D08.811.913.696.620.682.700.567.249.875 D12.644.360.450.169.875 D12.776.476.450.169.875
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Concept/Terms |
Mitogen-Activated Protein Kinase 6- Mitogen-Activated Protein Kinase 6
- Mitogen Activated Protein Kinase 6
- p97MAPK Protein
- MAPK6 Mitogen-Activated Protein Kinase
- MAPK6 Mitogen Activated Protein Kinase
- ERK3 Kinase
- Kinase, ERK3
- Extracellular Signal-Regulated Kinase 3
- Extracellular Signal Regulated Kinase 3
- p97(MAPK) Protein
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 6".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 6".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 6" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 6" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 6" by people in Profiles.
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Massart J, Sj?gren RJO, Egan B, Garde C, Lindgren M, Gu W, Ferreira DMS, Katayama M, Ruas JL, Barr?s R, O'Gorman DJ, Zierath JR, Krook A. Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism. Nat Commun. 2021 10 12; 12(1):5948.
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Brand F, Schumacher S, Kant S, Menon MB, Simon R, Turgeon B, Britsch S, Meloche S, Gaestel M, Kotlyarov A. The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology. Mol Cell Biol. 2012 Jul; 32(13):2467-78.
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Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M. Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5. J Biol Chem. 2006 Nov 17; 281(46):35511-9.
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Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M. Scaffolding by ERK3 regulates MK5 in development. EMBO J. 2004 Dec 08; 23(24):4770-9.