Transcription Factor TFIIB
"Transcription Factor TFIIB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA POLYMERASE II specific transcription factor. It plays a role in assembly of the pol II transcriptional preinitiation complex and has been implicated as a target of gene-specific transcriptional activators.
| Descriptor ID |
D035581
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| MeSH Number(s) |
D12.776.260.775.875.562 D12.776.930.930.875.562
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor TFIIB".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor TFIIB".
This graph shows the total number of publications written about "Transcription Factor TFIIB" by people in this website by year, and whether "Transcription Factor TFIIB" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor TFIIB" by people in Profiles.
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Virbasius CM, Holstege FC, Young RA, Green MR. Promoter-specific activation defects by a novel yeast TBP mutant compromised for TFIIB interaction. Curr Biol. 2001 Nov 13; 11(22):1794-8.
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Li XY, Virbasius A, Zhu X, Green MR. Enhancement of TBP binding by activators and general transcription factors. Nature. 1999 Jun 10; 399(6736):605-9.
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Huh JR, Park JM, Kim M, Carlson BA, Hatfield DL, Lee BJ. Recruitment of TBP or TFIIB to a promoter proximal position leads to stimulation of RNA polymerase II transcription without activator proteins both in vivo and in vitro. Biochem Biophys Res Commun. 1999 Mar 05; 256(1):45-51.
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Roberts SG, Choy B, Walker SS, Lin YS, Green MR. A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation. Curr Biol. 1995 May 01; 5(5):508-16.
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Roberts SG, Green MR. Activator-induced conformational change in general transcription factor TFIIB. Nature. 1994 Oct 20; 371(6499):717-20.
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Imbalzano AN, Zaret KS, Kingston RE. Transcription factor (TF) IIB and TFIIA can independently increase the affinity of the TATA-binding protein for DNA. J Biol Chem. 1994 Mar 18; 269(11):8280-6.