Species Specificity

"Species Specificity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.

Descriptor ID	D013045
MeSH Number(s)	G16.824
Concept/Terms	Species Specificity Species Specificity Species Specificities Specificities, Species Specificity, Species

Below are MeSH descriptors whose meaning is more general than "Species Specificity".

Biological Sciences [G]
Biological Phenomena [G16]
Species Specificity [G16.824]

Below are MeSH descriptors whose meaning is more specific than "Species Specificity".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Species Specificity" by people in this website by year, and whether "Species Specificity" was a major or minor topic of these publications.

Bar chart showing 241 publications over 30 distinct years, with a maximum of 15 publications in 2005 and 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	7	7
1997	0	10	10
1998	0	1	1
1999	0	7	7
2000	0	5	5
2001	0	7	7
2002	0	11	11
2003	0	11	11
2004	0	12	12
2005	0	15	15
2006	0	12	12
2007	0	6	6
2008	0	8	8
2009	0	13	13
2010	0	8	8
2011	0	13	13
2012	0	15	15
2013	0	11	11
2014	0	10	10
2015	0	9	9
2016	0	7	7
2017	0	4	4
2018	0	7	7
2019	0	11	11
2020	0	10	10
2021	0	1	1
2022	0	1	1
2024	1	2	3
2025	0	4	4
2026	0	2	2

Below are the most recent publications written about "Species Specificity" by people in Profiles.

Barbosa CRR, de Lacerda LB, Bettencourt PJG, Morrow D, Pereira DB, Aleshnick M, Mitchell JL, Poulton NC, Gomes C, Cordeiro LPB, Doumbia K, Ntalla C, Arama C, Zhao Z, Maia GC, Almeida GG, Schrimpf MR, Hart TF, Haumpy D, Medeiros-Rodrigues BC, Costa CM, Nicastri A, Gilbride RM, Schell JB, Kirtley P, Antonelli LRV, Gaiha GD, Hansen SG, Lieberman J, Gazzinelli RT, Niangaly M, Woodford J, Goldberg J, Fr?h K, Portugal S, Duffy PE, Ternette N, Wilder B, Hill AVS, Junqueira C. Identification of cross-stage, cross-species malaria CD8+ T cell antigens. Nature. 2026 Jul; 655(8123):747-757.

View in: PubMed
Gonzalez J, Genereux DP, Crouse K, Frishman B, G Hindle A, Karlsson E, B Madelaire C, Moreira L, Forbes V. New approaches to discovering epigenetic rules of homeostasis in diverse mammal species. BMC Genomics. 2026 Apr 10; 27(1).

View in: PubMed
Oomen ME, Fox AN, Gonzalez I, Molliex A, Papadopoulou T, Navarro P, Dekker J. Mitotic chromosomes harbor cell type- and species-specific structural features within a universal loop array conformation. Genome Res. 2025 08 01; 35(8):1733-1744.

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Kwaku GN, Jensen KN, Simaku P, Floyd DJ, Saelens JW, Reardon CM, Ward RA, Basham KJ, Hepworth OW, Vyas TD, Zamith-Miranda D, Nosanchuk JD, Vyas JM, Brown Harding H. Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation. PLoS Pathog. 2025 May; 21(5):e1012879.

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Lee HC, Akizawa H, Fissore RA. Roles of the EF-hand domain of PLCZ1 in establishing species-specific Ca2+ oscillations in mouse and rat fertilization?. Biol Reprod. 2025 04 13; 112(4):663-674.

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Pullen KM, Finethy R, Ko SB, Reames CJ, Sassetti CM, Lauffenburger DA. Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection. NPJ Syst Biol Appl. 2025 Feb 15; 11(1):19.

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Ali SA, Perera G, Laird J, Batorsky R, Maron MS, Rivas VN, Stern JA, Harris S, Chin MT. Single Cell Transcriptomic Profiling of MYBPC3-Associated Hypertrophic Cardiomyopathy Across Species Reveals Conservation of Biological Process But Not Gene Expression. J Am Heart Assoc. 2025 01 07; 14(1):e035780.

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Rivera Flores IV, Monopoli K, Jackson S, Echeverria D, O'Reilly D, Brown RH, Khvorova A. Near Sequence Homology Does Not Guarantee siRNA Cross-Species Efficacy. Nucleic Acid Ther. 2024 10; 34(5):234-244.

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Zhang W, Oh JH, Zhang W, Aldrich CC, Sirianni RW, Elmquist WF. Pharmacokinetics of Panobinostat: Interspecies Difference in Metabolic Stability. J Pharmacol Exp Ther. 2024 03 15; 389(1):96-105.

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Noh HJ, Turner-Maier J, Schulberg SA, Fitzgerald ML, Johnson J, Allen KN, H?ckst?dt LA, Batten AJ, Alfoldi J, Costa DP, Karlsson EK, Zapol WM, Buys ES, Lindblad-Toh K, Hindle AG. The Antarctic Weddell seal genome reveals evidence of selection on cardiovascular phenotype and lipid handling. Commun Biol. 2022 02 17; 5(1):140.

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