Species Specificity

"Species Specificity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.

Descriptor ID	D013045
MeSH Number(s)	G16.824
Concept/Terms	Species Specificity Species Specificity Species Specificities Specificities, Species Specificity, Species

Below are MeSH descriptors whose meaning is more general than "Species Specificity".

Biological Sciences [G]
Biological Phenomena [G16]
Species Specificity [G16.824]

Below are MeSH descriptors whose meaning is more specific than "Species Specificity".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Species Specificity" by people in this website by year, and whether "Species Specificity" was a major or minor topic of these publications.

Bar chart showing 239 publications over 30 distinct years, with a maximum of 15 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	9	9
1996	0	8	8
1997	0	11	11
1998	0	1	1
1999	0	7	7
2000	0	5	5
2001	0	6	6
2002	0	13	13
2003	0	11	11
2004	0	12	12
2005	0	15	15
2006	0	11	11
2007	0	7	7
2008	0	8	8
2009	0	12	12
2010	0	7	7
2011	0	14	14
2012	0	14	14
2013	0	10	10
2014	0	9	9
2015	0	9	9
2016	0	6	6
2017	0	4	4
2018	0	7	7
2019	0	8	8
2020	0	8	8
2021	0	1	1
2022	0	1	1
2024	2	1	3
2025	0	2	2

Below are the most recent publications written about "Species Specificity" by people in Profiles.

Lee HC, Akizawa H, Fissore RA. Roles of the EF-hand domain of PLCZ1 in establishing species-specific Ca2+ oscillations in mouse and rat fertilization?. Biol Reprod. 2025 Apr 13; 112(4):663-674.

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Pullen KM, Finethy R, Ko SB, Reames CJ, Sassetti CM, Lauffenburger DA. Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection. NPJ Syst Biol Appl. 2025 Feb 15; 11(1):19.

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Ali SA, Perera G, Laird J, Batorsky R, Maron MS, Rivas VN, Stern JA, Harris S, Chin MT. Single Cell Transcriptomic Profiling of MYBPC3-Associated Hypertrophic Cardiomyopathy Across Species Reveals Conservation of Biological Process But Not Gene Expression. J Am Heart Assoc. 2025 Jan 07; 14(1):e035780.

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Rivera Flores IV, Monopoli K, Jackson S, Echeverria D, O'Reilly D, Brown RH, Khvorova A. Near Sequence Homology Does Not Guarantee siRNA Cross-Species Efficacy. Nucleic Acid Ther. 2024 10; 34(5):234-244.

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Zhang W, Oh JH, Zhang W, Aldrich CC, Sirianni RW, Elmquist WF. Pharmacokinetics of Panobinostat: Interspecies Difference in Metabolic Stability. J Pharmacol Exp Ther. 2024 Mar 15; 389(1):96-105.

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Noh HJ, Turner-Maier J, Schulberg SA, Fitzgerald ML, Johnson J, Allen KN, H?ckst?dt LA, Batten AJ, Alfoldi J, Costa DP, Karlsson EK, Zapol WM, Buys ES, Lindblad-Toh K, Hindle AG. The Antarctic Weddell seal genome reveals evidence of selection on cardiovascular phenotype and lipid handling. Commun Biol. 2022 02 17; 5(1):140.

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Hart TM, Dupuis AP, Tufts DM, Blom AM, Starkey SR, Rego ROM, Ram S, Kraiczy P, Kramer LD, Diuk-Wasser MA, Kolokotronis SO, Lin YP. Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system. PLoS Pathog. 2021 07; 17(7):e1009801.

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Nagai J, Yu X, Papouin T, Cheong E, Freeman MR, Monk KR, Hastings MH, Haydon PG, Rowitch D, Shaham S, Khakh BS. Behaviorally consequential astrocytic regulation of neural circuits. Neuron. 2021 02 17; 109(4):576-596.

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Taher H, Mahyari E, Kreklywich C, Uebelhoer LS, McArdle MR, Mostr?m MJ, Bhusari A, Nekorchuk M, E X, Whitmer T, Scheef EA, Sprehe LM, Roberts DL, Hughes CM, Jackson KA, Selseth AN, Ventura AB, Cleveland-Rubeor HC, Yue Y, Schmidt KA, Shao J, Edlefsen PT, Smedley J, Kowalik TF, Stanton RJ, Axthelm MK, Estes JD, Hansen SG, Kaur A, Barry PA, Bimber BN, Picker LJ, Streblow DN, Fr?h K, Malouli D. In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome. PLoS Pathog. 2020 11; 16(11):e1008666.

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Yurkovetskiy L, Wang X, Pascal KE, Tomkins-Tinch C, Nyalile TP, Wang Y, Baum A, Diehl WE, Dauphin A, Carbone C, Veinotte K, Egri SB, Schaffner SF, Lemieux JE, Munro JB, Rafique A, Barve A, Sabeti PC, Kyratsous CA, Dudkina NV, Shen K, Luban J. Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. Cell. 2020 10 29; 183(3):739-751.e8.

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