Receptors, Antigen, T-Cell, alpha-beta

"Receptors, Antigen, T-Cell, alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules.

Descriptor ID	D016693
MeSH Number(s)	D12.776.543.750.705.816.824.825
Concept/Terms	Receptors, Antigen, T-Cell, alpha-beta Receptors, Antigen, T-Cell, alpha-beta Antigen Receptors, T-Cell, alpha-beta TcR alpha-beta TcR alpha beta alpha-beta, TcR T-Cell Receptor, alpha-beta T Cell Receptor, alpha beta alpha-beta T-Cell Receptor T-Cell Receptors, alpha-beta alpha-beta T-Cell Receptors Receptors, Antigen, T Cell, alpha beta T Cell Receptors, alpha beta Antigen T Cell Receptor, beta Chain Antigen T Cell Receptor, beta Chain T-Cell Receptors beta-Chain T Cell Receptors beta Chain beta-Chain, T-Cell Receptors T-Cell Receptor beta-Chain T Cell Receptor beta Chain beta-Chain, T-Cell Receptor T-Cell Receptors alpha-Chain T-Cell Receptors alpha-Chain T Cell Receptors alpha Chain alpha-Chain, T-Cell Receptors Antigen T Cell Receptor, alpha Chain T-Cell Receptor alpha-Chain T Cell Receptor alpha Chain alpha-Chain, T-Cell Receptor

Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell, alpha-beta".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Antigen [D12.776.543.750.705.816]
Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]
Receptors, Antigen, T-Cell, alpha-beta [D12.776.543.750.705.816.824.825]

Below are MeSH descriptors whose meaning is related to "Receptors, Antigen, T-Cell, alpha-beta".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell, alpha-beta".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in this website by year, and whether "Receptors, Antigen, T-Cell, alpha-beta" was a major or minor topic of these publications.

Bar chart showing 80 publications over 25 distinct years, with a maximum of 9 publications in 1999 and 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	2	2
1996	1	4	5
1997	1	1	2
1998	0	3	3
1999	5	4	9
2000	2	2	4
2001	0	1	1
2002	1	2	3
2003	1	3	4
2005	1	0	1
2006	0	2	2
2007	1	0	1
2008	5	4	9
2009	1	0	1
2010	2	1	3
2011	2	2	4
2012	3	2	5
2013	3	1	4
2014	4	0	4
2015	2	1	3
2016	0	1	1
2019	2	3	5
2020	2	0	2
2021	1	0	1
2023	0	1	1

Below are the most recent publications written about "Receptors, Antigen, T-Cell, alpha-beta" by people in Profiles.

Clark F, Gil A, Thapa I, Aslan N, Ghersi D, Selin LK. Cross-reactivity influences changes in human influenza A virus and Epstein Barr virus specific CD8 memory T cell receptor alpha and beta repertoires between young and old. Front Immunol. 2022; 13:1011935.

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Mordes JP, Cort L, Liu Z, Eberwine R, Blankenhorn EP, Pierce BG. T Cell Receptor Genotype and Ubash3a Determine Susceptibility to Rat Autoimmune Diabetes. Genes (Basel). 2021 06 01; 12(6).

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Cleveland SB, Huseby ES. Resolving the Instructions for a? T Cell Development. Immunity. 2020 12 15; 53(6):1126-1128.

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Gil A, Kamga L, Chirravuri-Venkata R, Aslan N, Clark F, Ghersi D, Luzuriaga K, Selin LK. Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor a and ? Repertoires. mBio. 2020 03 17; 11(2).

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Kamga L, Gil A, Song I, Brody R, Ghersi D, Aslan N, Stern LJ, Selin LK, Luzuriaga K. CDR3a?drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection. PLoS Pathog. 2019 11; 15(11):e1008122.

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Jiang W, Birtley JR, Hung SC, Wang W, Chiou SH, Macaubas C, Kornum B, Tian L, Huang H, Adler L, Weaver G, Lu L, Ilstad-Minnihan A, Somasundaram S, Ayyangar S, Davis MM, Stern LJ, Mellins ED. In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls. Nat Commun. 2019 11 20; 10(1):5247.

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Stadinski BD, Blevins SJ, Spidale NA, Duke BR, Huseby PG, Stern LJ, Huseby ES. A temporal thymic selection switch and ligand binding kinetics constrain neonatal Foxp3+ Treg cell development. Nat Immunol. 2019 08; 20(8):1046-1058.

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Wong EB, Gold MC, Meermeier EW, Xulu BZ, Khuzwayo S, Sullivan ZA, Mahyari E, Rogers Z, Kl?verpris H, Sharma PK, Worley AH, Lalloo U, Baijnath P, Ambaram A, Naidoo L, Suleman M, Madansein R, McLaren JE, Ladell K, Miners KL, Price DA, Behar SM, Nielsen M, Kasprowicz VO, Leslie A, Bishai WR, Ndung'u T, Lewinsohn DM. TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis. Commun Biol. 2019; 2:203.

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Spidale NA, Frascoli M, Kang J. ?dTCR-independent origin of neonatal ?d T cells prewired for IL-17 production. Curr Opin Immunol. 2019 06; 58:60-67.

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Gallagher MP, Berg LJ. Gene-enhancer variants reveal diverse TCR-mediated differentiation. Nat Immunol. 2017 04 18; 18(5):483-484.

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