Neurotransmitter Uptake Inhibitors
"Neurotransmitter Uptake Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects.
|Neurotransmitter Uptake Inhibitors
- Neurotransmitter Uptake Inhibitors
- Uptake Inhibitors, Neurotransmitter
- Reuptake Inhibitors, Neurotransmitter
- Inhibitors, Neurotransmitter Reuptake
- Neurotransmitter Reuptake Inhibitors
- Transmitter Uptake Inhibitors, Neuronal
- Inhibitors, Neurotransmitter Uptake
Below are MeSH descriptors whose meaning is more general than "Neurotransmitter Uptake Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Neurotransmitter Uptake Inhibitors".
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Below are the most recent publications written about "Neurotransmitter Uptake Inhibitors" by people in Profiles.
Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Dyrks T, Thiele A, Heneka MT. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits. Neurochem Int. 2010 Nov; 57(4):375-82.
Biezonski DK, Meyer JS. Effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity. J Neurochem. 2010 Feb; 112(4):951-62.
Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging. 2007 Aug; 28(8):1206-14.