"Protein Footprinting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes a protein cutting reagent or protease. Protein cleavage is inhibited where the proteins, or nucleic acids and protein, contact each other. After completion of the cutting reaction, the remaining peptide fragments are analyzed by electrophoresis.
| Descriptor ID |
D023302
|
| MeSH Number(s) |
E05.196.700.690 E05.393.760.705.685.690
|
| Concept/Terms |
Protein Footprints- Protein Footprints
- Footprint, Protein
- Protein Footprint
- Footprints, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Footprinting".
Below are MeSH descriptors whose meaning is more specific than "Protein Footprinting".
This graph shows the total number of publications written about "Protein Footprinting" by people in this website by year, and whether "Protein Footprinting" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Footprinting" by people in Profiles.
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Niu B, Mackness BC, Zitzewitz JA, Matthews CR, Gross ML. Trifluoroethanol Partially Unfolds G93A SOD1 Leading to Protein Aggregation: A Study by Native Mass Spectrometry and FPOP Protein Footprinting. Biochemistry. 2020 10 06; 59(39):3650-3659.
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Hainer SJ, Fazzio TG. Regulation of Nucleosome Architecture and Factor Binding Revealed by Nuclease Footprinting of the ESC Genome. Cell Rep. 2015 Oct 06; 13(1):61-69.
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Singh G, Ricci EP, Moore MJ. RIPiT-Seq: a high-throughput approach for footprinting RNA:protein complexes. Methods. 2014 Feb; 65(3):320-32.
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Rozovsky N, Butterworth AC, Moore MJ. Interactions between eIF4AI and its accessory factors eIF4B and eIF4H. RNA. 2008 Oct; 14(10):2136-48.